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Monomethylauristatin F （MMAF）
Inoa Kimia: (S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S) -3-methyl-2-(methylamino)butanamido)akā anamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic ʻakika Molecular Weight: 731.96 Formula: C39H65N5O8 CAS#: 141205-32-5 Solubility: DMSO a hiki i 20 mM Biological Activity Monomethyl auristatin F (MMAF) a i ʻole desmethyl-auristatin F he mea anti-tubulin e pale ana i ka mahele cell ma ka pale ʻana o ka tubulin. He ... -
Monomethyl Auristatin E (MMAE)
Inoa Kimia: (S)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2 -yl)amino)-1-methoxy-2-methyl-3-oxopropyl)p yrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimethyl-2-(S)-3-methyl-2-(methylamino)butanamido)butanamide Kaumaha Molecular: 717.98 Formula: C39H67N5O7 CAS: 474645-27-7 Solubility: DMSO a hiki i 20 mM Monomethyl Auristatin E he dolastatin-10 peptide derivative me ka hana antimitotic ikaika a me ka hana antineoplastic hiki ke ʻāpana o ka antibody...