Inoa Kimia:(S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S) -3-methyl-2-(methylamino)butanamido)akā anamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic ʻakika

Kaumaha Molekala:731.96
Kumu:C39H65N5O8
CAS#:141205-32-5
Hiki ke hoʻoheheʻe:DMSO a hiki i 20 mM

Hana Ola
ʻO Monomethyl auristatin F (MMAF) a i ʻole desmethyl-auristatin F he mea anti-tubulin e kāohi ana i ka mahele cell ma ka pale ʻana i ka polymerization o tubulin. He mea houauristatin mea hoʻopukame kahi phenylalanine C-terminal i hoʻopiʻi ʻia e hoʻemi ana i kāna hana cytotoxic i hoʻohālikelike ʻia me kāna mea i hoʻopaʻa ʻole ʻia, monomethyl auristatin E (MMAE). Eia kekahi, ʻo ka hui amino N-terminal wale nōʻekahimethyl substituent ma kahi o ʻelua e like me ka inAuristatin Fiho.