Orukọ kemikali: (S) - ((3R, 5s) -1 - ((1r, 2r) -3 - ((1s) -3 - ((1s) -3 - ((1s) -3 - ((1s) -3 - ((1s) -3 - -1) -1 -1 -1 -1-4-metpy-2-methyl-3-okiroptyl) p yrrolidin-1-yl) -3 -3 -3-mtluxy-5-methyl-1-ymthyl-2 - (
Iwuwo Molucular: 717.98
Agbekalẹ: c39h67N5O7
Cas: 474645-27-7
Solubia: DMSO to 20 mm

Monomethl auristatin e jẹ adolattin-10Pesede derivive pẹlu iṣẹ antimitotic ti o lagbara ati iṣẹ antileoplatic ti o pọju gẹgẹbi apakan ti antibody-ajecdonce conjugate (adc). Monomethl auristatin e (Mmes) Bins si tulini, awọn bulọọki Tulanizin pomulini, ati awọn abajade awọn iṣelọpọ macrotic ti mitotic ati imulo awọn sẹẹli iṣan ni ipele m. Lati dinku majele ati mu agbara pọ,MmesTi wa ni conjugated, nipasẹ Asopọ ti a crivaferable Pelertide Pexpable, si Antibody Monoclonal ti o jẹ pataki fanilara kan. Olumulo naa jẹ idurosinsin ni Ilu Mimieu ṣugbọn o ni imurasilẹ ni imurasilẹ lati tu silẹMmesAwọn atẹle ati ailapọ ti adc nipasẹ awọn sẹẹli ti o fojusi.