1. Intshayelelo yeExenatideiacetate
Exenatide acetate, kunye nezithethantonye ze Extendin-4; I-UNII-9P1872D4OL, lunye uhlobo lomgubo omhlophe. Le khemikhali yeyoluhlu lweeMveliso zePeptide.
2. Ubuthi be-acetate ye-Exenatide
I-acetate ye-Exenatide inezi datha zilandelayo:
Izinto eziphilayo | Uhlobo loVavanyo | Indlela | Idosi exeliweyo (Ithamo eliQhelekileyo) | Isiphumo | Umthombo |
---|---|---|---|---|---|
inkawu | LD | ngaphantsi kwesikhumba | > 5mg/kg (5mg/kg) | Ingcali yetyhefu. Umqulu. 48, iphe. 324, 1999. | |
impuku | LD | ngaphantsi kwesikhumba | > 30mg/kg (30mg/kg) | Ingcali yetyhefu. Umqulu. 48, iphe. 324, 1999. |
3. Ukusetyenziswa kwe-acetate ye-Exenatide
Exenatide Acetate(I-CAS NO.141732-76-5) iyeza (i-incretin mimetics) evunyiweyo (Apr 2005) yonyango lwe-diabetes mellitus type 2.
Ifomula yemolekyuli:
c184h282n50o60s
ubunzima bemolekyuli:
4186.63 g/mol
Ulandelelwano :
h-his-gly-glu-gly-thr-phe-thr-ser-asp-leu-ser-lys-gln-met-glu-glu-glu-ala-val-arg-leu-phe-ile-glu- trp-leu-lys-asn-gly-gly-pro-ser-ser-gly-ala-pro-pro-ser-nh2 ityuwa yeacetate