Ifomula yemolekyuli:

I-C76H104N18O19S2

Ubunzima beMolekyuli:

1637.90 g/mol

Inombolo yeCAS:

38916-34-6 (umnatha)

Ukugcinwa kwexesha elide:

-20 ± 5°C

Izithethantonye:

I-Somatostatin-14; I-SRIF-14;
Ukukhutshwa kweSomatotropin-Inhibiting Factor; I-SRIF

Ulandelelwano:

I-H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH ityuwa yeacetate (Disulfide bond)

Imiba yesicelo:

Ukopha kwesilonda
I-gastritis ene-hemorrhagic
I-postoperative pancreatic kunye ne-duodenal fistulae
I-Variceal hemorrhage

Into esebenzayo:

I-Somatostatin (SRIF) i-inhibitor ye-hormone yokukhula yokukhululwa kwi-pituitary yangaphambili kwaye ngoko ke umchasi we-GRF.I-Somatostatin icinezela ukukhululwa kweentlobo zezinye iihomoni ezibandakanyekayo ekulawuleni imisebenzi ebalulekileyo ye-physiological of the tract gastrointestinal. I-Somatostatin iphinda ivimbele ukuveliswa kwe-TSH.I-Somatostatin yi-peptide ye-amino acid eyi-14 ebizwa ngokuba yi-pituitary GROWTH HORMONE release, ebizwa ngokuba yi-somatotropin release-inhibiting factor. Ibonakaliswa kwiinkqubo ze-nervous central kunye ne-peripheral, amathumbu, kunye namanye amalungu. I-SRIF inokuthintela ukukhululwa kwe-THYROID-STIMULATING HORMONE; IPROLACTIN; INSULIN; kunye neGLUCAGON ngaphandle kokusebenza njenge-neurotransmitter kunye neuromodulator. Kwinani leentlobo ezibandakanya abantu, kukho uhlobo olongezelelweyo lwe-somatostatin, i-SRIF-28 kunye ne-14-amino acid extension kwi-N-terminal.

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