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Monomethylauristatin F (MMAF)
Jina la Kemikali: (S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S) -3-methyl-2-(methylamino)butanamido)lakini anamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic asidi Uzito wa Masi: 731.96 Mfumo: C39H65N5O8 CAS#: 141205-32-5 Umumunyifu: DMSO hadi 20 mm Shughuli za Kibiolojia Monomethyl auristatin F (MMAF) au desmethyl-auristatin F ni kinza-tubulini kikali ambacho huzuia mgawanyiko wa seli. ya tubulini. Ni... -
Monomethyl Auristatin E (MMAE)
Jina la Kemikali: (S)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2 -yl)amino)-1-methoxy-2-methyl-3-oxopropyl)p yrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamide Uzito wa Masi: 717.98 Fomula: C39H67N5O7 CAS: 474645-27-7 Umumunyifu: DMSO hadi 20 mM Monomethyl Auristatin E ni derivative ya peptidi ya dolastatin-10 yenye shughuli kali ya antimitotiki na uwezekano wa shughuli ya antineoplastic kama sehemu ya kingamwili...