Foromo ea molek'hule:
Setšoantšo sa C52H74N16O15S2
Boima ba Molek'hule:
1227.39 g/mol
Nomoro ea CAS:
14636-12-5 (nete)
Polokelo ea nako e telele:
-20 ± 5°C
Tatelano:
H-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 letsoai la acetate
(Bond ea Disulfide)
Mekha ea Kopo:
Ho tsoa mali a mangata (acute variceal hemorrhage)
Hepatorenal syndrome
Norepinephrine-resistant septic shock - ha e e-so be kopo e amohetsoeng
Ntho e sebetsang:
Terlipressinke analogue ea maiketsetso ea vasopressin 'me e sebelisoa e le setlhare sa vasoactive taolong ea hypotension.
Terlipressine emela prodrug, e fetoloa ho (Lys8) - vasopressin (LVP) ka mor'a ho tlosoa ha N-terminal.
triglycine ka har'a vivo. Terlipressin e na le nako e telele ea ts'ebetso le boemo bo botle ba polokeho ho feta LVP ea motsoako oa motsoali.
Boemo ba Khoebo:
Lebitso la k'hamphani: Shenzhen JYMed Technology Co., Ltd.
Selemo sa Thehiso: 2009
Motse-moholo: 89.5 limilione tse RMB
Sehlahisoa se ka sehloohong: Oxytocin Acetate,Vasopressin Acetate,Desmopressin Acetate,Terlipressin acetate,Caspofungin acetate, Micafungin sodium, Eptifibatide acetate, Bivalirudin TFA, Deslorelin Acetate,Glucagon Acetate,Histrelin Acetate,Lilitace Acetate ,Degarelix Acetate,Buserelin Acetate,Cetrorelix Acetate,Goserelin
Acetate, Argireline Acetate, Metrixyl Acetate,Snap-8,…..
Re ikitlaelletsa ho tsoela pele ka mekhoa e mecha ea theknoloji e ncha ea peptide synthesis le ts'ebetso ea ts'ebetso, 'me sehlopha sa rona sa tekheniki se na le boiphihlelo bo fetang lilemo tse leshome ho peptide synthesis.JYM e rometse tse ngata ka katleho.
ea ANDA peptide APIs le lihlahisoa tse entsoeng ka CFDA mme li na le litokelo tse fetang mashome a mane tse lumelletsoeng.
Setsi sa rona sa peptide se Nanjing, profinseng ea Jiangsu mme se thehile setsi sa lisekoere-mithara tse 30,000 ho latela tataiso ea cGMP. Setsi sa tlhahiso se hlahlobiloe le ho hlahlojoa ke bareki ba malapeng le ba machaba.
Ka boleng ba eona bo babatsehang, theko ea tlhōlisano ka ho fetisisa le tšehetso e matla ea botekgeniki, JYM ha e fumane feela ho ananeloa bakeng sa lihlahisoa tsa eona ho tsoa mekhatlong ea Lipatlisiso le liindasteri tsa Pharmaceutical, empa hape e fetoha e mong oa barekisi ba tšepahalang ka ho fetisisa ba li-peptide Chaena,. JYM e inehetse ho ba e mong oa bafani ba li-peptide ba ka sehloohong lefatšeng haufinyane.