Foromo ea molek'hule:

Setšoantšo sa C76H104N18O19S2

Boima ba Molek'hule:

1637.90 g/mol

Nomoro ea CAS:

38916-34-6 (nete)

Polokelo ea nako e telele:

-20 ± 5°C

Synonymes:

Somatostatin-14; SRIF-14;
Somatotropin Release-Inhibiting Factor; SRIF

Tatelano:

H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH letsoai la acetate (Disulfide bond)

Mekha ea Kopo:

Ho tsoa mali a seso
Hemorrhagic gastritis
Ka mor'a opereishene ea pancreatic le duodenal fistula
Variceal hemorrhage

Ntho e sebetsang:

Somatostatin (SRIF) ke inhibitor ea kholo ea hormone e lokolloa ho tswa ho anterior pituitary 'me kahoo mohanyetsi oa GRF.Somatostatin e hatella ho lokolloa ha lihomone tse ling tse sa tšoaneng tse amehang ho laola mesebetsi ea bohlokoa ea' mele ea pampiri ea mala. Somatostatin e boetse e thibela tlhahiso ea TSH.Somatostatin ke 14-amino acid peptide e bitsoang ka bokhoni ba eona ba ho thibela ho lokolloa ha pituitary GROWTH HORMONE, eo hape e bitsoang somatotropin release-inhibiting factor. E hlahisoa tsamaisong ea methapo e bohareng le ea peripheral, mala, le litho tse ling. SRIF ka boela thibela ho lokolloa THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; le GLUCAGON ntle le ho sebetsa joalo ka neurotransmitter le neuromodulator. Mefuteng e mengata e kenyeletsang batho, ho na le mofuta o eketsehileng oa somatostatin, SRIF-28 e nang le katoloso ea 14-amino acid ho N-terminal.

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