Lebitso la lik'hemik'hale: (S) -n - ((3r, 4s, 5s) -1 - ((((((((((1r, 2r) -3 - - hydroxy-1-pichenylpropan-2 -yl) amino) -1-mety-2-methyl-3-oxopropyl) p yrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamide
Boima ba Molecular: 717.98
Foromo: C39H67n5O7
Cas: 474645-27-7-7
Fulubity: DMSO ho fihla ho 20 mm

Monomethyl auuristatin e is aDolastatin-10Peptide e matlafatsang le ts'ebetso ea bo-bong e nang le ts'ebetso le ketsahalo e ka bang karolo ea antiboggle e antiboget (ADC). Monomethyl Auuristatin E (MMAE MMAE) lichineng tsa tubulin, lithibelo tsa tubulanication, 'me li sitisa sebopeho sa microtatic le ho ts'oara lisele tsa lisele tsa li-spor tsa potoloho ea li-sileor. Ho fokotsa chefo le ho holisa katleho,MMAE MMAEe kopane, ka peelide e hlahang e hlakileng ea Pepdide, ho apornod ea monoclonal e loanelang hlahala ea mokuli ka ho khetheha. The Linker e tsitsitse mokhoeng o eketsehileng empa o hloekisoa habonolo ho lokolloaMMAE MMAEho latela ho tlama le ho kenella ha ADC ka lisele tsa sepheo.