Lebitso la lik'hemik'hale:(S)-2-((2R,3R)-3-(S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S) -3-methyl-2-(methylamino)butanamido)empa anamido) -3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic asiti

Boima ba Molek'hule:731.96
Foromo:C39H65N5O8
CAS #:141205-32-5
Sollubility:DMSO ho fihla ho 20 mmM

Mosebetsi oa Likokoana-hloko
Monomethyl auristatin F (MMAF) kapa desmethyl-auristatin F ke moemeli oa anti-tubulin o thibelang karohano ea lisele ka ho thibela polymerization ea tubulin. Ke ntho e nchaauristatine e nkiloenge nang le C-terminal phenylalanine e qosoang e fokotsang ts'ebetso ea eona ea cytotoxic ha e bapisoa le molekane oa eona ea sa lefelloeng, monomethyl auristatin E (MMAE). Ho phaella moo, sehlopha sa amino sa N-terminal se na le feelangoemethyl substituent sebakeng sa tse peli joalo ka inauristatine Fka boyona.