Magaca kiimikada: (S) -N - ((3R, 4s, 5s) -1 - ((S) - ((1R, 2r, 2r) -1-hydrtopropran-2 -Key) Amino) -1-Methoxy-2-methyly-3-oxpropyl) p Yrrolidin-1-yl) -3-Methoxy-
Miisaanka Moleculal: 717.98
Qaaciddada: c39h67n5o7
CAS: 474645-27-7
Naafanimada: DMSSO ilaa 20 mm

Mornadyl auristaatin e waa adolastathin-10Petteive waxay kaheleysaa dhaqdhaqaaq xanuun lintitotic oo awood leh iyo nashaad ka hortag ah oo ka hortag ah oo qayb ka ah antibody-daroogada conjugate (ADC). Monomethyl auristaatin e (Mmae) Ku xidhnaado tubulin, baloogyada paulinka tubulin-ka, oo ay ka hortagaan abuurista microtububir, taas oo keenta in carqalad lagu daro kiniisadda mitotic Spindle iyo xariga unugyada burooyinka ee wareega MERT ee wareega MERT. Si loo yareeyo sunta oo kor u qaad wax ku ool ah,MmaeWaa la isku qaxay, iyada oo loo marayo xariirka Petpide oo la daadi karo, oo loo maro monoclonal-ka monoclonal ah oo si gaar ah u beegsanaya burooyinka bukaanka. Linker-ka waa mid deggan tahay in Milieu-ka dib-u-soo-baxa laakiin si fudud loogu dhejiyo siideyntaMmaeKa dib xiritaanka iyo gudaha ee ku dhex jira ADC unugyada bartilmaameedka.