Magaca kiimikada:(Yaasha) -2 - ((2r, 3R) -3 - ((S) --1 - ((((3R, 4s, 5s) -4 - ((s) - ((yada) -3-methyly-2- ((methylamino) Buthamindo) laakiin anaamido) -3-Metroxy-5-methylheptoninl) Pyrrodin-2-yl) -3-Metroxy-2-methexy-2-ylylpropanamido) -3-phenyllpropanoic aashito

Miisaanka Moleculal:731.96
Qaaciddada:C39h65N5O8
CAS #:141205-32-5
Xoobi:Dmso ilaa 20 mm

Waxqabadka bayoolojiga
Monometyl Auriristatin f (MMAF) ama DesMethyl-Auriristatin f waa wakiilka kahortaga-tubulilin ee horjoogsanaysa qaybta unugyada iyadoo la joojinayo polymomemization poumpulin. Waa wax cusubAuriristatin soosaaridaIyada oo ay ku eedeeyaan 'c-terrinal phenylalanine' ee lagu soo oogay oo lagu soo bandhigayo howlaheeda cytotoxic-ka marka loo barbar dhigo dhiggiisa aan la soo gaarin, monometyl auristaatin e (mmae). Intaa waxa u dheer, kooxda N-Terminal Amino waxay leedahay oo keliyahal / kowmethyl beatluent halkii ay ka ahaan lahaayeen laba sidiiAuriristatin flafteeda.