Dzina la Chene: (S) -n - (3r, 4s, 5s) -1 - (1 - (1) - 1R)-1-PHDROXY-2 -Ye) amino) -1-methoxy-2-methyl-3-oxOopyl) p Yorroloidin-1-YL) -3-a Methoxy-5-Oxetheptan-4-yl) -3
Kulemera kwa maselo: 717.98
Fomula: C39h67N5O7
Cas: 474645-7-7
Kusungunuka: DMSO mpaka 20 mm

Monomethyl auristatin e ndiDolastatin-10Puptity Druvity ndi ntchito yamphamvu yamphamvu komanso ntchito ya antineoplacticstics monga gawo la antibody-mankhwala conjugate (ADC). Monomethyl auristatin e (Mmae) Amamangiriza Tubalin, blocks bukulin polymerization, ndipo amaletsa kusokonekera kwa mitrotuble, komwe kumapangitsa kusokonezeka kwa mitoko ya mitokoti ndi kumangidwa kwa maselo otupa mu gawo la cell. Kuchepetsa zoopsa ndikukulitsa bwino,MmaeAmakhala otayidwa, kudzera pa traptide ya peptide, kwa antiblody omwe amayambitsa chotupa cha wodwala. Linker ndi yokhazikika muzowonjezera kwa mabamira koma imamasulidwa mosavutaMmaeKutsatira kumangirira ndi kusinthika kwa ADC ndi maselo ozungulira.