Dzina la Chemical:(S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S) -3-methyl-2-(methylamino)butanamido)koma anamido) -3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic asidi

Kulemera kwa Molecular:731.96
Fomula:C39H65N5O8
CAS #:141205-32-5
Kusungunuka:DMSO mpaka 20 mm

Ntchito Zachilengedwe
Monomethyl auristatin F (MMAF) kapena desmethyl-auristatin F ndi anti-tubulin wothandizira omwe amalepheretsa kugawanika kwa maselo poletsa polymerization ya tubulin. Ndi chatsopanoauristatin zochokerayokhala ndi C-terminal phenylalanine yomwe imalepheretsa ntchito yake ya cytotoxic poyerekeza ndi mnzake wosalipidwa, monomethyl auristatin E (MMAE). Kuphatikiza apo, gulu la amino la N-terminal lili ndi zokhaimodzimethyl m'malo mwa awiri monga inauristatin Fyokha.