1ml: 4μg / 1ml: 15μg Mphamvu

Chizindikiro:

MASONYEZO NDI NTCHITO

Hemophilia A: Desmopress mu Acetate jekeseni 4 mcg/mL amasonyezedwa kwa odwala hemophilia A ndi factor VIII coagulant ntchito milingo yoposa 5%.

Desmopress mu jakisoni wa acetate nthawi zambiri imakhala ndi hemostasis kwa odwala omwe ali ndi hemophilia A panthawi ya opaleshoni komanso pambuyo pa opaleshoni ikaperekedwa mphindi 30 isanachitike.

Desmopress mu jakisoni wa acetate imasiyanso magazi mu hemophilia A odwala omwe ali ndi zochitika zodziwikiratu kapena zovulala zobwera chifukwa cha zoopsa monga hemarthroses, intramuscular hematomas kapena mucosal magazi.

Desmopress mu jakisoni wa acetate sikuwonetsedwa pochiza hemophilia A yokhala ndi gawo VIII coagulant zochita zofananira kapena zosakwana 5%, kapena pochiza hemophilia B, kapena odwala omwe ali ndi ma antibodies a factor VIII.

Muzochitika zina zachipatala, zingakhale zomveka kuyesa desmopress mu jekeseni wa acetate kwa odwala omwe ali ndi chiwerengero cha VIII pakati pa 2% mpaka 5%; komabe, odwalawa ayenera kuyang'aniridwa mosamala. Matenda a von Willebrand (Mtundu Woyamba): Desmopres s mu jakisoni wa acetate 4 mcg/mL amasonyezedwa kwa odwala omwe ali ndi matenda a von Willebrand (Mtundu Woyamba) omwe ali ndi chiwerengero cha VIII choposa 5%. Desmopress mu jakisoni wa acetate nthawi zambiri imakhala ndi hemostasis kwa odwala omwe ali ndi matenda a von Willebrand ofatsa kapena ochepa panthawi ya opaleshoni komanso pambuyo pa opaleshoni akamaperekedwa mphindi 30 isanachitike.

Desmopress mu jakisoni wa acetate nthawi zambiri imasiya kutuluka magazi pang'onopang'ono kapena pang'ono odwala a von Willebrand omwe amavulala modzidzimutsa kapena chifukwa chovulala monga hemarthroses, intramuscular hematomas kapena mucosal magazi.

Odwala omwe ali ndi matenda a von Willebrand omwe sangayankhe ndi omwe ali ndi matenda a homozygous von Willebrand omwe ali ndi factor VIII coagulant ndi factor VIII von.

Willebrand factor antigen milingo yochepera 1%. Odwala ena angayankhe mosiyanasiyana malinga ndi mtundu wa chilema chomwe ali nacho. Nthawi ya magazi ndi factor VIII coagulant ntchito, ristocetin cofactor ntchito, ndi von Willebrand factor antigen ziyenera kufufuzidwa panthawi ya desmopress mu jakisoni wa acetate kuonetsetsa kuti milingo yokwanira ikukwaniritsidwa.

Desmopress mu jakisoni wa acetate samawonetsedwa pochiza matenda oopsa a von Willebrand's (Mtundu Woyamba) komanso ngati pali umboni wa mawonekedwe achilendo amtundu wa factor VIII antigen.

Diabetes Insipidus: Desmopress mu jakisoni wa acetate 4 mcg/mL akuwonetsedwa ngati antidiuretic m'malo mankhwala poyang'anira chapakati (cranial) matenda a shuga insipidus komanso pakuwongolera kwakanthawi kwa polyuria ndi polydipsia kutsatira kupwetekedwa mutu kapena opaleshoni m'dera la pituitary.

Desmopress mu jakisoni wa acetate ndiyosathandiza pochiza nephrogenic shuga insipidus.

Desmopress mu acetate imapezekanso ngati kukonzekera kwa intranasal. Komabe, njira yoperekera iyi ikhoza kusokonezedwa ndi zinthu zosiyanasiyana zomwe zingapangitse kuti mphuno ikhale yosagwira ntchito kapena yosayenera.

Izi ndi monga kusayamwa bwino m'mphuno, kutsekeka kwa m'mphuno ndi kutsekeka, kutuluka m'mphuno, kupweteka kwa mucosa wamphuno, ndi atrophic rhinitis. Kuperekera m'mphuno kungakhale kosayenera pamene pali chidziwitso chosokonezeka. Kuphatikiza apo, maopaleshoni a cranial, monga transsphenoidal hypophysectomy, amapanga nthawi yomwe njira ina yoperekera chithandizo ikufunika monga momwe zimakhalira kunyamula m'mphuno kapena kuchira kuchokera ku opaleshoni.

ZOTHANDIZA

Desmopress mu jakisoni wa acetate 4 mcg/mL imatsutsana ndi anthu omwe amadziwika kuti ali ndi hypersensitivity ku desmopress mu acetate kapena mbali iliyonse ya desmopress mu jakisoni wa acetate 4 mcg/mL.

Desmopress mu jakisoni wa acetate imatsutsana ndi odwala omwe ali ndi vuto laimpso lapakati kapena lalikulu (lotanthauzidwa ngati chilolezo cha creatinine chochepera 50ml/min).

Desmopress mu jakisoni wa acetate imatsutsana ndi odwala omwe ali ndi hyponatremia kapena mbiri ya hyponatremia.