Ingoa matū:(S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S) -3-methyl-2-(methylamino)butanamido)engari anamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic waikawa

Taumaha rāpoi:731.96
Tātai:C39H65N5O8
CAS#:141205-32-5
Wairewa:DMSO ki te 20 mM

Mahi Koiora
Ko te Monomethyl auristatin F (MMAF) ko te desmethyl-auristatin F he kaihoko anti-tubulin e aukati ana i te wehenga pūtau ma te aukati i te polymerization o te tubulin. He mea houauristatin pärönakime te phenylalanine C-terminal ka whakahekehia tana mahi cytotoxic ka whakatauritea ki tana hoa kore utu, monomethyl auristatin E (MMAE). I tua atu, ko te roopu amino N-terminal he anakekotahimethyl substituent hei utu mo te rua hei rotoauristatin Fake.