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Monomethylauristatin F MMAF）
Nomen chemicum: (S) -2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S) -3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidinum-2-yl) -3-methoxy-2-methylpropanamido) -3-phenylpropanoicum acidum Molecular pondus: 731.96 Formulae: C39H65N5O8 CAS#: 141205-32-5 Solubilitas: DMSO usque ad 20 mM Activitas biologica Monomethyl auristatin F (MMAF) seu desmethyl-auristatin F est agens anti-tubulinum quod divisionem cellularum impedit polymerizationem interclusit. tubulin. Aliquam est... -
Monomethyl Auristatin E (MMAE)
Nomen chemicum: (S)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2 -yl)amino)-1-methoxy-2-methyl-3-oxopropyl)p yrrolidin-1-yl) -3-methoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamide Pondus molecular: 717.98 Formula: C39H67N5O7 CAS: 474645-27-7 Solubilitas: DMSO usque ad 20 mM Monomethyl Auristatin E est dolastatin-X peptide derivativa cum potentia antimitotica et potentia antineoplastica ut pars anticorporis...