Aha kemịkalụ:(S)-2-((2R,3R)-3-((S) -1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S) -3-methyl-2- (methylamino) butanamido) butanamido) -3-methoxy-5-methylheptanoyl) pyrrolidin-2-yl) -3-methoxy-2-methylpropanamido) -3-phenylpropanoic acid.

Arọ Molecular:731.96
Usoro:C39H65N5O8
CAS#:141205-32-5
Solubility:DMSO ruo 20 mmM

Omume ndu
Monomethyl auristatin F (MMAF) ma ọ bụ desmethyl-auristatin F bụ ihe mgbochi tubelin nke na-egbochi nkewa cell site na igbochi polymerization nke tubulin. Ọ bụ ọhụrụauristatin ewepụtaraya na phenylalanine C-terminal ebubo nke na-ebelata ọrụ cytotoxic ya ma e jiri ya tụnyere nke ya na-akwụghị ụgwọ, monomethyl auristatin E (MMAE). Na mgbakwunye, otu N-terminal amino group nwere naanịotumethyl dochie anya abụọ dị ka inauristatin Fonwe ya.