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Monomethylauristatin F (MMAF)
Non chimik: (S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S) -3-methyl-2-(methylamino)butanamido) men anamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic asid Molekilè Pwa: 731.96 Fòmil: C39H65N5O8 CAS#: 141205-32-5 Solibilite: DMSO jiska 20 mM Byolojik Aktivite Monomethyl auristatin F (MMAF) oswa desmethyl-auristatin F se yon ajan anti-tubulin ki anpeche divizyon selilè a pa bloke polymerization. nan tubulin. Li se yon... -
Monomethyl Auristatin E (MMAE)
Non chimik: (S)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2 -yl)amino)-1-metoksi-2-methyl-3-oxopropyl)p yrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamid Pwa Molekilè: 717.98 Fòmil: C39H67N5O7 CAS: 474645-27-7 Solibilite: DMSO jiska 20 mM Monomethyl Auristatin E se yon derive peptide dolastatin-10 ak aktivite antimitotik ki pisan ak aktivite antineoplastik potansyèl kòm yon pati nan yon antikò...