Lub npe tshuaj:(S)-2-((2R,3R)-3-(S)-1-(((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S)) -3-methyl-2-(methylamino)butanamido) tab sis anamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic kua qaub

Molecular Luj:731.96 ib
Formula:C39H65N5O8
CAS Nr:141205-32-5
Solubility:DMSO mus txog 20 mM

Kev ua lom lom
Monomethyl auristatin F (MMAF) los yog desmethyl-auristatin F yog cov tshuaj tiv thaiv tubulin uas inhibits cell faib los ntawm thaiv cov polymerization ntawm tubulin. Nws yog ib qho tshiabtshuaj aristatin derivativenrog rau tus nqi C-terminal phenylalanine uas txo qis nws cov kev ua haujlwm cytotoxic piv rau nws cov khoom siv tsis tau them nqi, monomethyl auristatin E (MMAE). Tsis tas li ntawd, N-terminal amino pawg tsuas muajibmethyl hloov pauv tsis yog ob yam li hauvauristatin Fnws tus kheej.