Sunan sunadarai: (S) -n - (3r, 4s, 5s) -1 - (((s) -1 - ((1s, 2r) -1-hydroxy-1-phenlproprop 1 -yl) amino) -1-metoxy-2-methyl-3-oxopropyl) p yrololdin-1-yl methyl-5-methyl-1-yl metheptan-4-ylylam-2 - (((s)-3- (((s)-2- (((s) -3
Nauyi na kwayoyin: 717.98
Formulla: c39h67n5o7
CAS: 474645-27-7
Sanarwar: DMSO har zuwa 20 mm

Monomethyl auristatin eDoLastatin-10Peptide nutsuwa tare da kayan aikin rigakafi da kuma ƙarfin motsa jiki na antineoplastic a matsayin wani ɓangare na maganin ƙwayar cuta (ADC). Monomethyl abarristatin e (Mmae) The tubulin, toshe tubulin polymerization, kuma yana hana Microtubule formashe, wanda ke haifar da rikicewar ƙwayar cuta ta mitrotic a cikin tsarin sel na sel. Don rage guba da kuma kara inganci,Mmaean conjugated, ta hanyar mai rufin cin gashin kansa, zuwa antiblonal otholy wanda musamman ke niyyar cutar marassa lafiya. Mai rufin yana da tsayayye a cikin karin miniieu amma ana cike da tsabta don sakiMmaeBiye da karfi da kuma cikin gida na ADC ta hanyar sel manufa.