Sunan sunadarai:(S) -2 - ((2r, 3r) -3 - (((s) -1 - ((3r, 4s, 4s) -4 - (((s) -4 -3-methyl-2- (methylamano) bututun Anamido na maɗaci

Nauyi na kwayoyin:731.96
Formuldu:C39H65N5O8O
CAS #:141205-32-5
Sanarwar:Dmso har zuwa 20 mm

Aikin halittu
Monomethyl auristatin f (mmaf) ko desmethyl-auristatin f shine wakilin anti-tubulin wanda ke hanzarta rarraba sel ta toshe polymerization na tubulin. Sabo neakistatin abin kirkiTare da cajin C-Ternylalaine wanda ke gabatar da ayyukan Cytotoxic idan aka kwatanta da takwaransa na kasa, Monomethyl auristatin e (mmae). Bugu da kari, da N-Termal amintaccen aminoɗayamethyl m maimakon biyu kamarauristatin fkanta.