Sunan Sinadari:(S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S) -3-methyl-2- (methylamino) butanamido) butanamido -3-methoxy-5-methylheptanoyl) pyrrolidin-2-yl) -3-methoxy-2-methylpropanamido) -3-phenylpropanoic acid

Nauyin Kwayoyin Halitta:731.96
Formula:Saukewa: C39H65N5O8
CAS#:141205-32-5
Solubility:DMSO har zuwa 20 mM

Ayyukan Halittu
Monomethyl auristatin F (MMAF) ko desmethyl-auristatin F wakili ne na anti-tubulin wanda ke hana rarraba tantanin halitta ta hanyar toshe polymerization na tubulin. Wani sabo neauristatin na asalitare da cajin C-terminal phenylalanine wanda ke rage ayyukan cytotoxic idan aka kwatanta da takwaransa wanda ba a caji ba, monomethyl auristatin E (MMAE). Bugu da kari, rukunin amino N-terminal yana da kawaidayaMai maye gurbin methyl maimakon biyu kamar inAuristatin Fkanta.