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Monomethylauristatin F (MMAF)
Gemyske namme: (S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S) -3-methyl-2-(methylamino)butanamido)but anamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic soer Molekulêre Gewicht: 731.96 Formule: C39H65N5O8 CAS #: 141205-32-5 Oplosberens: DMSO oant 20 mM Biologyske aktiviteit Monomethyl auristatin F (MMAF) of desmethyl-auristatin F is in anty-tubulin-selleferdieling dy't it blokkearjen fan 'e sellenferdieling fan tubuline fan tubulin. It is in... -
Monomethyl Auristatin E (MMAE)
Gemyske namme: (S)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-fenylpropan-2 -yl)amino)-1-methoxy-2-methyl-3-oxopropyl) p yrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamide Molekulêr gewicht: 717.98 Formule: C39H67N5O7 CAS: 474645-27-7 Oplosberens: DMSO oant 20 mM Monomethyl Auristatin E is in dolastatin-10 peptide-derivaat mei krêftige antimitotyske aktiviteit en potinsjele antineoplastyske aktiviteit as ûnderdiel fan antylichem ...