Amagama angukhiye
Ifomula ye-Molecular:
I-C76H104N18O19S2
I-Relative Molecular Mass:
1637.90 g/mol
Inombolo ye-CAS:
38916-34-6 (inetha)
Isitoreji Sesikhathi eside:
-20 ± 5°C
Amazwi afanayo:
I-Somatostatin-14; I-SRIF-14;
Isici Esivimbela Ukukhishwa kweSomatotropin; I-SRIF
Ukulandelana:
I-H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH usawoti we-acetate (isibopho se-Disulfide)
Izinkambu zohlelo lokusebenza:
Ukopha kwesilonda
I-gastritis ene-hemorrhagic
I-postoperative fistula ye-pancreatic kanye ne-duodenal
I-variceal hemorrhage
Into esebenzayo:
I-Somatostatin (SRIF) iyi-inhibitor yokukhululwa kwe-hormone yokukhula kusukela ku-anterior pituitary futhi ngakho-ke umphikisi we-GRF.I-Somatostatin icindezela ukukhululwa kwamanye amahomoni ahlukahlukene ahilelekile ekulawuleni imisebenzi ebalulekile ye-physiological of the tract gastrointestinal. I-Somatostatin iphinde ivimbele ukukhiqizwa kwe-TSH.I-Somatostatin iyi-peptide engu-14-amino acid ebizwa ngokuthi ikhono layo lokuvimbela ukukhululwa kwe-pituitary GROWTH HORMONE, okubizwa nangokuthi i-somatotropin release-inhibiting factor. Ivezwa ohlelweni lwezinzwa oluphakathi nendawo kanye ne-peripheral, amathumbu, nezinye izitho. I-SRIF ingaphinda ivimbele ukukhululwa kwe-THYROID-stimulating HORMONE; I-PROLACTIN; I-insulin; kanye ne-GLUCAGON ngaphandle kokusebenza njenge-neurotransmitter kanye ne-neuromodulator. Ezinhlotsheni eziningi ezihlanganisa abantu, kukhona uhlobo olwengeziwe lwe-somatostatin, i-SRIF-28 ene-14-amino acid extension e-N-terminal.
Iphrofayela Yenkampani: