I-Nonapeptide-1 iyi-nonapeptide eyodwa eyenza isikhumba sibe mhlophe. Ingasetshenziswa ezinhlotsheni ezahlukahlukene zokucwenga noma imikhiqizo yokulungisa indawo.
Vimbela ukuhlanganiswa kwe-melanin ngokuphazamisa isenzo se-tyrosinase kuma-melanocytes. Yehlisa i-hyperpigmentation futhi ukhanyise izindawo ezimnyama ezilinyazwe ilanga nezifo ezithile.
Phakamisa i-melanocyte stimulating hormone (MSH). I-MSH iyanda ngesikhathi sokukhulelwa, ngenxa yezimo ezithile zezokwelapha (isb. isifo sikashukela, isifo sika-Addison), kanye nangenxa yokuchayeka kakhulu elangeni.
I-Nonapeptide-1, ekuhlanganiseni kuka-200 ug/mL, iyakwazi ukuvimbela ngokugcwele ukwakheka kwe-melanin kusikhunta.
Ekugxilweni kwe-micromolar eyi-100, i-nonapeptide-1 ingavimbela u-25-35% womsebenzi we-tyrosinase kumamodeli ezilwane futhi inganciphisa okuqukethwe kwe-melanin kuma-melanocyte ngo-27-43%
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