U-Erica Prouty, u-PharmD, ungusokhemisi ochwepheshe osiza iziguli ngemithi nezinsizakalo zekhemisi eNyakatho Adams, Massachusetts.
Ezifundweni zezilwane ezingezona ezomuntu, i-semaglutide iboniswe ukuthi ibangele izicubu ze-C-cell yegilo kumagundane. Kodwa-ke, akucaci ukuthi lobu bungozi budlulela nakubantu. Kodwa-ke, i-semaglutide akufanele isetshenziswe kubantu abanomlando womuntu siqu noma womndeni we-medullary thyroid cancer noma kubantu abane-multiple endocrine neoplasia type 2 syndrome.
I-Ozempic (semaglutide) iyisidakamizwa sikadokotela esisetshenziswa kanye nokudla nokuzivocavoca ukulawula amazinga kashukela egazini kubantu abanesifo sikashukela sohlobo 2. Ibuye isetshenziselwe ukunciphisa ingozi yezenzakalo ezimbi kakhulu zenhliziyo njenge-stroke noma isifo senhliziyo kubantu abadala abanesifo sikashukela sohlobo lwe-2 nesifo senhliziyo.
I-ozone ayiyona i-insulin. Isebenza ngokusiza amanyikwe ukuthi akhiphe i-insulini lapho amazinga kashukela egazini ephezulu futhi ngokuvimbela isibindi ekwenzeni nokukhipha ushukela omningi. I-ozone ibuye ibambezele ukuhamba kokudla esiswini, inciphise isifiso sokudla futhi ibangele ukuncipha kwesisindo. I-Ozempic ingeyesigaba sezidakamizwa ezibizwa ngokuthi i-glucagon-like peptide 1 (GLP-1) agonists receptor.
I-Ozempic ayelaphi isifo sikashukela sohlobo loku-1. Ukusetshenziswa ezigulini ezine-pancreatitis (ukuvuvukala kwamanyikwe) akuzange kufundwe.
Ngaphambi kokuba uqale ukusebenzisa i-Ozempic, funda ipheshana lemininingwane yesiguli nencwadi yakho kadokotela bese ubuza udokotela wakho noma usokhemisi noma yimiphi imibuzo ongase ube nayo.
Qiniseka ukuthi uthatha lo muthi njengoba uyalelwe. Abantu ngokuvamile baqala ngethamo eliphansi kakhulu futhi banyuse kancane kancane njengoba beqondiswa umhlinzeki wabo wezempilo. Nokho, akufanele ushintshe umthamo wakho we-Ozempic ngaphandle kokukhuluma nochwepheshe bakho bezempilo.
I-Ozempic iwumjovo ongaphansi kwesikhumba. Lokhu kusho ukuthi ijovwa ngaphansi kwesikhumba sethanga, ingalo yangaphezulu, noma yesisu. Abantu ngokuvamile bathola umthamo wabo wamasonto onke ngosuku olufanayo lweviki. Umhlinzeki wakho wokunakekelwa kwezempilo uzokutshela ukuthi ungajova kuphi umthamo wakho.
Isithako se-Ozempic, i-semaglutide, siyatholakala futhi ngethebhulethi ngaphansi kwegama lomkhiqizo i-Rybelsus nangelinye uhlobo lomjovo ngaphansi kwegama lomkhiqizo elithi Wegovy. Ungasebenzisi izinhlobo ezahlukene ze-semaglutide ngesikhathi esisodwa.
Buza umhlinzeki wakho wezempilo ukuthi kufanele uwuhlole kangaki ushukela wakho wegazi. Uma ushukela wakho wegazi uphansi kakhulu, ungase uzwe ukugodola, indlala, noma isiyezi. Umhlinzeki wakho wezempilo uzokutshela ukuthi welaphe kanjani ushukela ophansi egazini, ngokuvamile ngenani elincane lejusi ye-apula noma amaphilisi eglucose asebenza ngokushesha. Abanye abantu basebenzisa iglucagon kadokotela ngomjovo noma isifutho samakhala ukwelapha izimo eziphuthumayo ezinzima ze-hypoglycemia.
Gcina i-Ozempic ephaketheni lokuqala esiqandisini, evikelekile ekukhanyeni. Ungasebenzisi amapeni aphelelwe yisikhathi noma afriziwe.
Ungasebenzisa futhi ipeni izikhathi eziningana ngenaliti entsha kumthamo ngamunye. Ungalokothi usebenzise izinaliti zokujova. Ngemuva kokusebenzisa ipeni, susa inaliti bese ubeka inaliti esetshenzisiwe esitsheni esibukhali ukuze ulahlwe kahle. Iziqukathi zokulahla ama-Sharps zivame ukutholakala emakhemisi, izinkampani ezihlinzeka ngemithi, nakubahlinzeki bezempilo. Ngokusho kwe-FDA, uma isitsha sokulahla izinto ezibukhali singatholakali, ungasebenzisa isiqukathi sasendlini esihlangabezana nalezi zidingo ezilandelayo:
Uma usuqedile ukusebenzisa ipeni, buyisela ikepisi bese uyibuyisela esiqandisini noma ezingeni lokushisa elivamile. Kugcine kude nokushisa noma ekukhanyeni. Lahla ipeni ezinsukwini ezingama-56 ngemuva kokusetshenziswa kokuqala noma uma kusele ngaphansi kuka-0.25 milligrams (mg) (njengoba kukhonjisiwe kwikhawunta yomthamo).
Gcina i-Ozempic ikude nezingane nezilwane ezifuywayo. Ungalokothi wabelane nabanye ngepeni le-Ozempic, ngisho noma ushintsha inaliti.
Abahlinzeki bezempilo bangase basebenzise ilebula engaphandle kwe-Ozempic, okusho ukuthi ezimeni ezingahlonzwanga ngokuqondile i-FDA. I-Semaglutide nayo ngezinye izikhathi isetshenziselwa ukusiza abantu ukuphatha isisindo sabo ngokusebenzisa inhlanganisela yokudla nokuzivocavoca.
Ngemuva komthamo wokuqala, i-Ozempic ithatha usuku olulodwa kuya kwezintathu ukufinyelela emazingeni aphezulu kakhulu emzimbeni. Nokho, i-Ozempic ayiwehlisi ushukela ngethamo lokuqala. Kungase kudingeke ukuthi uhlolwe ushukela wakho ngemva kwamasonto ayisishiyagalombili wokwelashwa. Uma umthamo wakho ungasebenzi kulesi sigaba, umhlinzeki wakho wokunakekelwa kwezempilo angase andise umthamo wakho weviki futhi.
Lokhu akulona uhlu oluphelele lwemiphumela emibi, eminye imiphumela emibi ingase yenzeke. Uchwepheshe wezokunakekelwa kwempilo angakutshela ngemiphumela engemihle. Uma uhlangabezana neminye imiphumela, xhumana nomhlinzeki wakho wokunakekelwa kwezempilo. Ungabika imiphumela emibi ku-FDA kokuthi fda.gov/medwatch noma ngokushayela ku-1-800-FDA-1088.
Shayela umhlinzeki wakho wezempilo ngokushesha uma unemiphumela emibi kakhulu. Uma izimpawu zakho ziyingozi empilweni noma ucabanga ukuthi udinga usizo lwezempilo oluphuthumayo, shayela u-911. Imiphumela emibi kakhulu kanye nezimpawu zayo ingase ihlanganise okulandelayo:
Bika izimpawu kumhlinzeki wakho wokunakekelwa kwezempilo noma ufune usizo oluphuthumayo uma kudingeka. Shayela udokotela wakho ngokushesha uma unezimpawu zesimila se-thyroid, okuhlanganisa:
I-ozone ingase ibangele eminye imiphumela emibi. Shayela umhlinzeki wakho wezempilo uma unezinkinga ezingajwayelekile ngenkathi uthatha lo muthi.
Uma uhlangabezana nemiphumela engemihle kakhulu, wena noma umhlinzeki wakho wokunakekelwa kwezempilo ningathumela umbiko ngoHlelo Lokubika Izenzakalo Ezimbi ze-FDA ze-MedWatch noma ushayele (800-332-1088).
Umthamo walo muthi uzohluka ezigulini ezihlukene. Landela izikhombisi-ndlela zikadokotela wakho kulebula. Ulwazi olungezansi luhlanganisa kuphela umthamo omaphakathi walo muthi. Uma umthamo wakho uhlukile, ungawushintshi ngaphandle uma udokotela wakho ekutshela ukuthi wenze njalo.
Inani lomuthi owuphuzayo lincike emandleni omuthi. Futhi, imithamo oyithathayo usuku ngalunye, isikhathi esivunyelwe phakathi kwemithamo, nokuthi uthatha isikhathi esingakanani umuthi kuncike enkingeni yezokwelapha oyisebenzisela umuthi.
Kwezinye izimo, kungase kudingeke ushintshe noma ulungise ukwelashwa nge-Ozempic. Abanye abantu kungase kudingeke baqaphele lapho bethatha lo muthi.
Ucwaningo lwezilwane okungezona olwabantu lubonisa ukuthi ukuchayeka ku-semaglutide kungabangela ukulimala okungenzeka kumntwana. Kodwa-ke, lezi zifundo azisebenzisi izifundo zabantu futhi azisebenzi kubantu.
Uma ukhulelwe noma uhlela ukukhulelwa, sicela uxhumane nomhlinzeki wakho wezempilo ukuze uthole iseluleko. Kungase kudingeke ukuthi uyeke ukusebenzisa i-Ozempic okungenani izinyanga ezimbili ngaphambi kokuthi ukhulelwe. Abantu abaseminyakeni yokuzala kufanele basebenzise ukulawulwa kokuzalwa okusebenzayo ngenkathi bethatha i-Ozempic futhi okungenani izinyanga ezimbili ngemva komthamo wokugcina.
Uma uncelisa, sicela uthintane nochwepheshe bakho bezempilo ngaphambi kokusebenzisa i-Ozempic. Akwaziwa ukuthi u-Ozempic udlula yini obisini lwebele.
Abanye abantu abadala abaneminyaka engu-65 nangaphezulu bazwela kakhulu ku-Ozempic. Kwezinye izimo, ukuqala ngethamo eliphansi futhi kancane kancane ukwandisa kungase kuzuze abantu asebekhulile.
Uma ugeja umthamo we-Ozempic, yithathe ngokushesha ngangokunokwenzeka phakathi nezinsuku ezinhlanu zedosi eqiwe. Bese uqalisa kabusha isimiso sakho samasonto onke. Uma sekudlule izinsuku ezingaphezu kwezinhlanu, yeqa umthamo futhi uqale kabusha umthamo wakho ngosuku oluhleliwe olujwayelekile lomthamo wakho.
Ukweqisa kwe-Ozempic kungase kubangele isicanucanu, ukuhlanza, noma ushukela ophansi egazini (hypoglycemia). Kuye ngezimpawu zakho, ungase unikezwe ukunakekelwa okusekelayo.
Uma ucabanga ukuthi wena noma omunye umuntu kungenzeka niphuze ngokweqile ku-Ozempic, shayela umhlinzeki wakho wokunakekelwa kwezempilo noma isikhungo sokulawula ubuthi (800-222-1222).
Kubaluleke kakhulu ukuthi udokotela wakho ahlole ukuqhubeka kwakho njalo ukuze aqiniseke ukuthi lo muthi usebenza kahle. Ukuhlolwa kwegazi nomchamo kungase kudingeke ukuze kuhlolwe imiphumela engemihle.
Tshela udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Ungawuphuzi lo muthi okungenani izinyanga ezi-2 ngaphambi kokuthi uhlele ukukhulelwa.
Ukunakekelwa okuphuthumayo. Kwesinye isikhathi ungadinga ukunakekelwa okuphuthumayo ngezinkinga ezibangelwa isifo sikashukela. Kufanele uzilungiselele lezi zimo eziphuthumayo. Kutuswa ukuthi uhlale ugqoke isongo se-Medical Identification (ID) noma umgexo. Futhi, phatha esikhwameni sakho noma uphathe umazisi othi unesifo sikashukela kanye nohlu lwayo yonke imithi yakho.
Lo muthi ungandisa ingozi yokuthuthukisa izimila zegilo. Tshela udokotela wakho ngokushesha uma unesigaxa noma ukuvuvukala entanyeni noma emphinjeni, uma unenkinga yokugwinya noma ukuphefumula, noma uma izwi lakho lihosha.
I-pancreatitis (ukuvuvukala kwamanyikwe) kungenzeka lapho usebenzisa lo muthi. Shayela udokotela wakho ngokushesha uma uzwa ubuhlungu obukhulu obungalindelekile besisu, ukugodola, ukuqunjelwa, isicanucanu, ukuhlanza, umkhuhlane, noma isiyezi.
Shayela udokotela wakho ngokushesha uma unesisu esibuhlungu, imfiva ephindaphindayo, ukuqunjelwa, noma ukuphuzi kwamehlo noma isikhumba. Lokhu kungase kube izimpawu zezinkinga ze-gallbladder njengama-gallstones.
Lo muthi ungadala i-retinopathy yesifo sikashukela. Xhumana nodokotela wakho uma unombono okhubazekile noma ezinye izinguquko zombono.
Lo muthi awubangeli i-hypoglycemia (ushukela wegazi ophansi). Kodwa-ke, ushukela wegazi ophansi ungenzeka lapho i-semaglutide isetshenziswa neminye imithi yokwehlisa ushukela wegazi, kufaka phakathi i-insulin noma i-sulfonylureas. Ukwehla kukashukela egazini kungenzeka futhi uma ubambezeleka noma weqa ukudla noma ukudla okulula, uzivocavoca ngaphezu kokujwayelekile, uphuza utshwala, noma ungakwazi ukudla ngenxa yokucanuzela kwenhliziyo noma ukuhlanza.
Lo muthi ungabangela ukungezwani okukhulu komzimba, okuhlanganisa i-anaphylaxis ne-angioedema, okungaba yingozi empilweni futhi kudinga ukunakwa ngokushesha. Shayela udokotela wakho ngokushesha uma uhlakulela ukuqubuka, ukulunywa, ukuhwalala, ukuphefumula kanzima, inkinga yokugwinya, noma ukuvuvukala kwezandla zakho, ubuso, umlomo, noma umphimbo ngenkathi usebenzisa le mithi.
Lo muthi ungabangela ukwehluleka kwezinso okukhulu. Shayela udokotela wakho ngokushesha uma unegazi emchameni wakho, ukwehla komchamo wakho, ukunyakazisa kwemisipha, isicanucanu, ukuzuza kwesisindo esisheshayo, ukuquleka, i-coma, ukuvuvukala kobuso bakho, amaqakala, noma izandla, noma ukukhathala okungavamile noma ubuthakathaka.
Lo muthi ungase ukhuphule izinga lokushaya kwenhliziyo yakho lapho uphumule. Shayela udokotela wakho ngokushesha uma unenhliziyo esheshayo noma eqinile.
I-Hyperglycemia (ushukela ophakeme) kungenzeka uma ungawuphuzi ngokwanele noma ungawusebenzisi umthamo womuthi oqeda isifo sikashukela, udle ngokweqile noma ungalandeli uhlelo lwakho lokudla, unomkhuhlane noma izifo, noma ungawuvivinyi umzimba ngendlela evamile. ngabe.
Lo muthi ungabangela ukucasuka, ukucasuka, noma okunye ukuziphatha okungajwayelekile kwabanye abantu. Kungase futhi kubangele abanye abantu ukuba babe nemicabango nokuthambekela kokuzibulala, noma bacindezeleke kakhulu. Tshela udokotela wakho uma unemizwa engazelelwe noma enamandla, okuhlanganisa imizwa yokwethuka, intukuthelo, ukucasuka, ubudlova, noma ukwesaba. Tshela udokotela wakho ngokushesha uma wena noma umnakekeli wakho nibona noma yimiphi yale miphumela emibi.
Ungathathi eminye imithi ngaphandle kokuthi uyalelwe udokotela wakho. Lokhu kuhlanganisa imithi kadokotela kanye ne-over-the-counter (OTC), kanye nezithako zemithi noma zamavithamini.
Abanye abantu bangase baqaphele mayelana nokuchaza i-ozone uma umhlinzeki wakho wokunakekelwa kwezempilo enquma ukuthi kuphephile. Le mibandela elandelayo ingase idinge ukuthi uthathe i-Ozempic ngokuqapha okukhulu:
I-Ozone ingadala i-hypoglycemia. Ukuthatha i-Ozempic neminye imithi yokwehlisa ushukela kungase kwenyuse ingozi yoshukela osegazini (ushukela ophansi). Kungase kudingeke ukuthi ulungise umthamo weminye imithi, njenge-insulin noma eminye imithi esetshenziselwa ukwelapha isifo sikashukela.
Ngenxa yokuthi i-ozone ibambezela ukuphuma kwesisu, ingaphazamisa ukumuncwa kwemithi yomlomo. Buza umhlinzeki wakho wezempilo ukuthi ungayihlela kanjani eminye imithi ngenkathi uthatha i-Ozempic.
Eminye imithi ingase yenyuse ingozi yokuba nenkinga yezinso uma iphuzwa ne-Ozempic. Le mithi ihlanganisa:
Lolu akulona uhlu oluphelele lokusebenzisana kwezidakamizwa. Okunye ukusebenzisana kwezidakamizwa kungenzeka. Tshela umhlinzeki wakho wokunakekelwa kwezempilo ngayo yonke imithi oyiphuzayo, okuhlanganisa nemithi kanye nemithi etholakala ezitolo kanye namavithamini noma izithasiselo. Lokhu kuqinisekisa ukuthi umhlinzeki wakho wokunakekelwa kwezempilo unolwazi aludingayo ukuze akunikeze i-Ozempic ngokuphepha.