I-Linaclotide

Incazelo emfushane:


  • Igama Lomkhiqizo:I-Linaclotide
  • Inombolo yeCas:851199-59-2
  • I-Molecular Formula:I-C59H79N15O21S6
  • Isisindo samangqamuzana:1526.8 g/mol
  • Ukulandelana:I-NH2-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH
  • Ukubukeka:Impushana emhlophe
  • Isicelo:Isetshenziselwa ukwelapha i-irritable bowel syndrome ngokuqunjelwa kanye nokuqunjelwa okungapheli ngaphandle kwesizathu esaziwayo
  • Iphakheji:Ngokwezidingo zekhasimende
  • Imininingwane Yomkhiqizo

    Omaka bomkhiqizo

    Amagama angukhiye

    • I-LinaclotideIsisekelo
    • intengo ethengekayo kakhulu
    • I-CAS# 851199-59-2

    Imininingwane Esheshayo

    • Igama lomkhiqizo: I-Linaclotide
    • Inombolo ye-Cas: 851199-59-2
    • I-Molecular Formula: C59H79N15O21S6
    • Ukubukeka: impushana emhlophe
    • Isicelo: isetshenziselwa Ukwelapha ukuqunjelwa
    • DeliveryTime: ukuthunyelwa ngokushesha
    • I-PackAge: ngokuya ngezidingo zekhasimende
    • Itheku: Shenzhen
    • Amandla okukhiqiza: 1 Kilogram/Inyanga
    • Ubumsulwa: 98%
    • Isitoreji: 2~8℃. ivikelwe ekukhanyeni
    • Ezokuthutha: ngendiza
    • UmkhawuloInombolo: 1 Gram

    Ukuphakama

     

    umkhiqizi we-peptide ochwepheshe e-china.
    izinga eliphezulu nge-gmp grade
    ngezinga elikhulu ngentengo yokuncintisana
    imikhiqizo yethu ihlanganisa: i-generic bulk peptide apis, i-cosmetic peptide, ama-peptide angokwezifiso kanye nama-peptide ezilwane.

     

    Imininingwane

     

    Umkhiqizo: I-Linaclotide
    Igama elifanayo: I-Linaclotide Acetate
    Inombolo ye-CAS: 851199-59-2
    I-Molecular Formula: C59H79N15O21S6
    Isisindo se-molecule: 1526.8
    Ukubukeka: Impushana emhlophe
    Ubumsulwa: >98%
    Ukulandelana: NH2-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH

    I-Linaclotide iyi-synthetic, i-amino acid peptide eyishumi nane kanye ne-agonist yohlobo lwe-guanylate cyclase yamathumbu C (GC-C), ehlobene ngokuhlelekile nomndeni we-guanylin peptide, ene-secretagogue, i-analgesic kanye nemisebenzi yokulambisa. Lapho isetshenziswa ngomlomo, i-linaclotide ibopha futhi ivule ama-GC-C receptors asendaweni ekhanyayo ye-epithelium yamathumbu. Lokhu kwandisa ukugcwala kwe-intracellular cyclic guanosine monophosphate (cGMP), etholakala ku-guanosine triphosphate (GTP). I-cGMP yenza kusebenze isilawuli se-cystic fibrosis transmembrane conductance (CFTR) futhi ikhuthaze ukukhishwa kwe-chloride ne-bicarbonate kulume lwamathumbu. Lokhu kukhuthaza ukuphuma kwe-sodium ku-lumen futhi kubangele ukwanda koketshezi lwamathumbu emathunjini. Lokhu ekugcineni kusheshisa ukuhamba kwe-GI kokuqukethwe kwamathumbu, kuthuthukisa ukuhamba kwamathumbu futhi kukhulule ukuqunjelwa. Ukwenyuka kwamazinga e-cGMP e-extracellular kungase futhi kube nomphumela we-antinociceptive, ngokusebenzisa indlela engakacaciswanga ngokugcwele, engabandakanya ukuguqulwa kwama-nociceptors atholakala ku-colonic afferent pain fibers. I-Linaclotide imuncwa kancane epheshaneni le-GI.

    Iphrofayela Yenkampani:
    Igama lenkampani: Shenzhen JYMed Technology Co., Ltd.
    Unyaka owasungulwa: 2009
    Inhlokodolobha: 89.5 Million RMB
    Umkhiqizo oyinhloko: I-Oxytocin Acetate,Vasopressin Acetate,Desmopressin Acetate,Terlipressin acetate,Caspofungin acetate,Micafungin sodium,Eptifibatide acetate,Bivalirudin TFA,Deslorelin Acetate,Glucagon Acetate,Histrelin Acetate,LietateglueAcetate ,Degarelix Acetate,Buserelin Acetate,Cetrorelix Acetate,Goserelin
    I-Acetate, i-Argireline Acetate, i-Metrixyl Acetate, i-Snap-8,…..
    Silwela ukuqhubeka nokuqamba izinto ezintsha kubuchwepheshe obusha be-peptide synthesis kanye nokwenza ngcono inqubo, futhi ithimba lethu lezobuchwepheshe linolwazi olungaphezu kweminyaka eyishumi ku-peptide synthesis.I-JYM ithumele ngempumelelo okuningi.
    ye-ANDA peptide APIs kanye nemikhiqizo eyenziwe nge-CFDA futhi inamalungelo obunikazi angaphezu kwamashumi amane agunyaziwe.
    Imboni yethu ye-peptide itholakala eNanjing, esifundazweni saseJiangsu futhi isimise indawo engamamitha-skwele angama-30,000 ngokuhambisana nomhlahlandlela we-cGMP. Indawo yokukhiqiza isihloliwe futhi yahlolwa yiwo womabili amaklayenti asekhaya nawamazwe ngamazwe.
    Ngekhwalithi yayo enhle kakhulu, intengo encintisana kakhulu nokusekelwa okuqinile kwezobuchwepheshe, i-JYM ayigcinanga ngokuthola ukuqashelwa kwemikhiqizo yayo ezinhlanganweni zoCwaningo kanye nezimboni Zemithi, kodwa futhi ibe omunye wabahlinzeki abathembekile bama-peptide e-China,. I-JYM inikezelwe ukuba ngomunye wabahlinzeki be-peptide abahamba phambili emhlabeni maduze nje.

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