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Awọn peptides ati awọn ọlọjẹ ti wa ni lilo pupọ lati tọju ọpọlọpọ awọn arun, ṣugbọn wọn nigbagbogbo ni abẹrẹ ati ipa wọn jẹ igba diẹ.Awọn ailagbara wọnyi ti awọn ẹya abinibi le yọkuro pẹlu iranlọwọ ti imọ-ẹrọ molikula, ṣugbọn eyi jẹ iṣẹ ti o nira.Awọn imọ-ẹrọ imọ-ẹrọ molikula, ni akọkọ ti a lo si hisulini ati ni bayi ti a lo ni aṣeyọri si ọpọlọpọ awọn biopharmaceuticals, nilo itọsẹ ti awọn peptides ati awọn ọlọjẹ lati awọn acids fatty.Awọn abuda kan pato ati ipo ti awọn acids fatty ti a so le pese awọn ọna ṣiṣe elongation oriṣiriṣi.Ni afikun, imọ-ẹrọ yii le pese igbesi aye idaji gigun lẹhin iṣakoso ẹnu ti awọn oogun peptide, le paarọ pinpin awọn peptides, ati pe o le ni agbara fun ifọkansi àsopọ.Pẹlu ailewu atorunwa ti awọn acids fatty ati awọn ohun-ini kemikali ti o ni alaye daradara, imọ-ẹrọ yii n pese ọna ti o wapọ si peptide ati wiwa oogun amuaradagba.
Gbogbo iye owo wa net.VAT yoo wa ni afikun nigbamii ni ibi isanwo.Awọn iṣiro owo-ori yoo ṣee ṣe ni ibi isanwo.
Muttenthaler, M., King, GF, Adams, DJ & Alewood, PF Trends ni peptide oògùn Awari. Muttenthaler, M., King, GF, Adams, DJ & Alewood, PF Trends ni peptide oògùn Awari.Muttenthaler, M., King, GF, Adams, DJ ati Alevud, PF Trends ni peptide oògùn Awari. Muttenthaler, M., Ọba, GF, Adams, DJ & Alewood, PF 多肽药物发现的趋势。 Muttenthaler, M., Ọba, GF, Adams, DJ & Alewood, PFMuttenthaler, M., King, GF, Adams, DJ ati Alevud, PF Trends ni peptide oògùn Awari.Orilẹ-ede šiši Aguntan oogun.20, 309-325 (2021).Atunwo yii da lori lọwọlọwọ ati awọn aaye iwaju ti iṣawari oogun peptide.
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Kurtzhals, P. et al.Abuda Albumin si hisulini acid acid-fatty: ijuwe ti awọn ibaraenisepo amuaradagba ligand-amuaradagba ati ibaraenisepo laarin isunmọ abuda ati akoko iṣe insulin ni vivo.biochemu.J. 312, 725–731 (1995).Iṣẹ yii jẹ akọkọ lati ṣe afihan ilosoke ninu igbesi aye idaji nitori sisopọ albumin si awọn peptides ti o wa lati awọn acids fatty.
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Kuna, M., Mahdi, F., Chade, AR & Bidwell, GL III Iwọn Molecular ṣe atunṣe awọn elegbogi elegbogi, ipinpinpin-ara, ati ifisilẹ kidirin ti ifijiṣẹ oogun biopolymer elastin-like polypeptide. Kuna, M., Mahdi, F., Chade, AR & Bidwell, GL III Iwọn Molecular ṣe atunṣe awọn elegbogi elegbogi, ipinpinpin-ara, ati ifisilẹ kidirin ti ifijiṣẹ oogun biopolymer elastin-like polypeptide. Kuna, M., Mahdi, F., Chade, AR & Bidwell, GL III ноподобного полипептида для доставки лекарственного средства. Kuna, M., Mahdi, F., Chade, AR & Bidwell, GL III Iwọn Molecular ṣe atunṣe awọn oogun elegbogi, ipinpinpin-ara, ati ifisilẹ kidirin ti biopolymeric elastin-like polypeptide fun ifijiṣẹ oogun. Ni afikun, M., MAHDI, F., CHAD, Aran, Aran, G 药物 弹性 药代 药代 动力 学 学 学 肾脏 肾脏 沉积 沉积 肾脏 肾脏 肾脏 肾脏 肾脏 肾脏 肾脏 肾脏 肾脏 肾脏 肾脏 肾脏 肾脏 肾脏. Kuna, M., Mahdi, F., Chade, AR & Bidwell, GL III Molecule 大小名行电影送送 biological polymer elastic protein sampleKuna, M., Mahdi, F., Chad, AR ati Bidwell, GL III.Pharmacokinetics, ipinpinpin ipinpinpin ati ifisilẹ kidirin ti biopolymeric elastin-bi polypeptides ti n ṣatunṣe iwọn moleku naa.Imọ Iroyin 8, 7923 (2018).
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Akoko ifiweranṣẹ: Oṣu Kẹsan-08-2022
