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Monomethylauristatin F (MMAF)
Ngaran Kimia: (S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimétil-2-((S) -3-métil-2-(methylamino)butanamido)tapi anamido)-3-metoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-fenilpropanoik asam Beurat Molekul: 731.96 Rumus: C39H65N5O8 CAS#: 141205-32-5 Kalarutan: DMSO nepi ka 20 mM Kagiatan Biologis Monomethyl auristatin F (MMAF) atawa desmethyl-auristatin F mangrupa agén anti-tubulin nu ngahambat division sél ku blocking nu. tina tubulin. Éta mangrupikeun ... -
Monométil Auristatin E (MMAE)
Ngaran Kimia: (S)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hidroksi-1-fenilpropan-2 -yl)amino)-1-métoksi-2-métil-3-okspropil)p yrrolidin-1-yl)-3-metoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimétil-2-(S)-3-methyl-2-(methylamino)butanamido)butanamide Beurat Molekul: 717.98 Rumus: C39H67N5O7 CAS: 474645-27-7 Kalarutan: DMSO nepi ka 20 mM Monomethyl Auristatin E nyaéta turunan péptida dolastatin-10 kalayan kagiatan antimitotik anu kuat sareng kagiatan antineoplastik poténsial salaku bagian tina antibodi ...