Nonapeptide-1 iganda rimwechete rinochenesa nonapeptide. Inogona kuiswa kune akasiyana marudzi ekuchena kana mavara ekugadzirisa zvigadzirwa.
Inhibit melanin synthesis nekukanganisa chiito che tyrosinase mu melanocytes. Deredza hyperpigmentation uye kurerutsa nzvimbo dzakasviba dzakakuvadzwa nezuva uye zvimwe zvirwere.
Kukanganisa ne melanocyte stimulating hormone (MSH). MSH inowedzera panguva yekuzvitakura, semugumisiro wemamwe mamiriro ehutano (eg chirwere cheshuga, chirwere cheAdisonison), uye semugumisiro wekunyanya kupisa kwezuva.
Nonapeptide-1, pahuwandu hwe200 ug/mL, inokwanisa kuvharidzira zvizere kuumbwa kwe melanin mufungi.
Pa100 micromolar concentration, nonapeptide-1 inogona kuvharidzira 25-35% ye tyrosinase chiitiko mumhando dzemhuka uye inogona kuderedza melanin yehuwandu hwe melanocytes ne 27-43%
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