FAQ

SemaglutideIs Glucagon-Senge Cheptide-1 (GLP-1) Receptor agonist inonyanya kushandiswa kudzora mwero weGlucose muVarwere vane type 2 chirwere chechipiri. GLP-1 is endoweus hormone yakavanzika neL-maseru mune diki mudumbu mushure mekudya, kutamba akawanda mabasa emuviri. Semaglutide inotarisa zviito zvehunhu zveGLP-1 uye inogadzirisa glucose uye uremu munzira nhatu huru:

1. Kusimudzira kweSisulin Secondon. Semaglutide inosimudzira maitiro aya nekumisa iyo GLP-1 Receptor, kunyanya kutamba basa rakakosha mukugadzirisa postprandial hyperglycemia. Iyi michina inogonesa semaglutudi kuti ideredze zvinobudirira post-yekudya ropa glucose spikes, kuvandudza zvese zvakazara glycemic kutonga muvarwere vane type yechipiri cheshuga.
2. Inhibition yeGlucaggon Secretion. Nekudaro, mune varwere vane type 2 chirwere cheshuga, chakavanzika cheGlucagon chinowanzoitika, zvichitungamira kune kukwidziridzwa kweropa glucose mazinga. Semaglutide inhibits iyo yakanyanya kunyoreswa yeGlucagon nekumisa iyo GLP-1 Receptor, Kuwedzera Kubatsira kuderedza kuderedza kweropa glucose mazinga eglucose.
3. Kuderera kwe gastric kusundwa. Mhedzisiro iyi isiri kungobatsira kudzora kweropa reropa glucose asi zvakare inowedzera kunzwa kwekuzara, kuderedza chikafu chakazara chekudya uye kubatsira pakurema maneja.

Kupfuura mhedzisiro yaro pane mutemo weropa, semaglutudi yakakoshesa kurema uremu, zvichiita kuti imhombwe yekufutisa kufutisa. Kurongeka kwehuremu kunobatsira kwete chete kune varwere veshuga asiwo kune vasina chirwere cheshuga vanhu vane furous.

Iyo yakasarudzika mechanism uye kiriniki kushanda kweiyo semaglutide inoita iyo isingabvumirwe mushonga mune chirwere cheshuga. Pamusoro pezvo, sekutsvagisa kunofambira mberi, izvo zvinogoneka zvekushandisa semabhiriyoni ekudzivirira kwemwoyo uye kurapwa kwekufutisa kuri kuwana hanya. Nekudaro, mimwe mhedzisiro, yakadai sekusagadzikana kwegastroint

LiraglutideIs Glucagon-Senge Peptide-1 (GLP-1) Receptor agonist inonyanya kushandiswa mukurapa kwerudzi rwechipiri uye kufutisa. GLP-1 ihormoni yakavanzika neL-maseru mune diki mudumbu mushure mekudya, uye inotora akawanda mabasa mukudzora glucose yeropa. Liraglutide inotora chiitiko cheGLP-1, kushandisa zvinoverengeka zvakakosha zvemuviri:

1. Kusimudzira kweSisulin Secondon. Liraglutide inosimbisa maitiro aya nekuvandudza iyo GLP-1 Receptor, kunyanya kuvandudza kweropa glucose kutonga panguva yekupindira hyperglycemia. Izvi zvinoita kuti liraglutulide yakashandiswa zvakanyanya mukugadzirisa post-yekudya kweropa glucose mazinga mune varwere vane mhando 2 chirwere cheshuga.
2. Inhibition yeGlucaggon Secretion. Nekudaro, mune varwere vane mhando 2 chirwere cheshuga, chakavanzika cheGlucagon chinowanzo kukwidziridzwa, chinotungamira kune yakakwira ropa glucose mazinga. Liraglutide inobatsira kudzora ropa glucose nekunyudza chigaro cheGlucaggon, kuderedza rombo glucuation dzimba dzeshuga mune varwere vane chirwere cheshuga.
3. Kunonoka gastric kudurura. Izvi zvisingaiti chete AIDS chete muropa reGlucose kudzora asi zvakare inowedzera kunzwa kwekuzara, kuderedza chikafu chekudya uye kubatsira varwere vanobata huremu hwavo.
4. Kurema manejimendi: Pamusoro pemhedzisiro yayo pane yeropa glucose kutonga, liraglutide yakaratidza kukosha kwehuremu hwakakosha. Izvi zvinonyanya kukonzerwa nemhedzisiro yayo pakudzora gastric kusundira uye kuwedzera masiyeti, zvichitungamira kuderedza caloric kudya uye kurema uremu. Nekuda kwekubudirira kwayo mukudzora uremu, liraglutide inoshandiswawo mukurapa kwekufutisa, kunyanya varwere vane chirwere cheshuga nekufutisa.
5. Cardiovascular Dziviriro. Izvi zvakakonzera kushandiswa kwaro kunowedzera kwakapararira muvarwere vane chirwere cheshuga uye chirwere chemwoyo.

Mukupfupikisa, liraglutide inodzora ropa glucose uye uremu kuburikidza nemhando dzakawanda mune dzimba dzeshuga mune chirwere cheshuga uye kuratidza zvinogona kurapwa nekureba kwekureba uye kuchengetedzwa kwemwoyo. Nekudaro, dzimwe mhedzisiro, dzakadai sekusvotwa, kurutsa, uye hypoglycemia, inogona kuitika panguva yekushandiswa kwereverengi, saka inofanira kushandiswa pasi pekurapa kwekurapa kuti ive yekuchengetedza uye kushanda.

TirzeedeIcho chinhu chinoshamisa-chiito chePeptie chePeptide chakanyatsogadzirirwa kuyamwisa nguva imwe chete Iyi tual Receptor inosungira inopa tirzede yakasarudzika kiriniki zvakanakira muChinese Type 2 chirwere cheshuga uye kugadzirisa uremu.

1. GLP-1 Receptor Agonism. Tirzeelide inosimudzira izvi zvinokonzeresa neAkpating GLP-1 Receptors, ichibatsira kunyatso kuderedza ropa reGlucose Pamusoro pezvo, GLP-1 Receptor activation inowedzera masaga, kuderedza kudya kwekudya uye kubatsira pakurema uremu.
2. Gip receptor agonism. Tirzepatide inowedzera kudzikisira Insulin Secretion neIctinging Gip Recepts uye ine mhedzisiro yemafuta tishu metabolism. Ichi chiitiko chechiitiko ichi chinopa tirzepatide mukana wakakura mukuvandudza insulin kunzwa, kuderedza ropa glucose mazinga, uye kugadzirisa uremu.
3. Kunonoka kusungirwa gastric kudurura. Izvi zvinoitika hazvingabatsira chete kudzora ropa glucose asi zvakare zvinowedzera kunzwa kwekuzara, kuwedzera kuderedza kudya kwechikafu.
4. Kurema manejimendi. Zvidzidzo zveClinic zvakaratidza kuti tirzepatide inogona kuderedza zvakanyanya uremu, izvo zvinonyanya kubatsira kune mhando 2 varwere veshuga vanofanirwa kudzora huremu hwavo.

Chimiro chemuzvimisikidzwa cheTiriepatide chinopa New Inorapeutic Option Intoct Type 2 chirwere cheshuga. Pasinei nemhando dzayo dzakakosha, dzimwe mhedzisiro, sekusagadzikana kwegastrointestinari, inogona kuitika panguva yekushandiswa kweTirzepatide, saka inofanira kushandiswa kutariswa kwekurapa.

OxetocinIcho chisikwa chinoitika chePeptide hormone yakashongedzwa muiyo hypothalamus uye yakachengetwa uye yakaburitswa neyekupedzisira pituitary gland. Iyo inotora yakakosha basa mune yekadzi kubereka system, kunyanya panguva yekushanda uye nguva yepashure pepashure. Basa rekutanga reOxyTocin ndeyekukurudzira chiuteve chemhasuru contractions nekusunga kune oxytocin Receptors pamasero anotsiga echibereko. Ichi chiitiko chakakosha kuti utange uye kuchengetedza maitiro ekubatikana.

Pakati pekushanda, sezvo mucheche achifamba kuburikidza neyekuzvarwa canal, kusunungurwa kweOxytocin Kuwedzera, kutungamira kune yakasimba uye rwiyo rwechibereki chibvumirano chinobatsira kuburitsa mwana. Kana kufambira mberi kwechisikigo kwebasa kunononoka kana kusimbiswa, synthetic oxytocin inogona kutumirwa zvine mutsindo nehutano mupi wehutano hwekutsamwisa chibvumirano uye kukwidzirisa maitiro evashandi. Maitiro aya anozivikanwa seyakagadzirwa basa.

Pamusoro pekunyengedza kwevashandi, oxytoin inoshandiswa zvakanyanya kudzora postpartum horparhage, yakajairika uye inogona kukanganisa njodzi mushure mekubereka mwana. PostPartum Horrhage kazhinji anowanzoitika kana chiberekechi ichi chikotadza kubatikana zvinobudirira mushure mekutakura. Nekuwedzera uterine contrace contraction, oxytof inobatsira kudzikisa kurasikirwa kweropa, nekudaro kudzikisa njodzi kune hutano hwaamai kunokonzerwa nekubuda ropa kwakanyanya.

Kupfuurirazve, oxytoxcin vanoita basa rakakura mukuyamwisa. Kana mucheche anoyamwa paya nipple's nipple, oxytoin inoburitswa, ichikonzera mhiri kwemukaka kuchibvumirano uye kusundira mukaka kuburikidza nemakaka, kufambisa mukaka ejekiseni. Kuita uku kwakakosha pakubudirira kwekuyamwisa, uye oxytoin dzimwe nguva zvinoshandiswa kubatsira vanaamai vanowana matambudziko panguva yekuwirirana.

Kupfuura, oxytocin mushonga unonyatsosarudzika mumidziyo, nekukuvara kwakapararira mukufambisa, kudzora postpartum hemorrhage, uye kutsigira nekuyamwisa. Nepo oxytoin kazhinji kazhinji kushandiswa, kutungamira kwaro kunofanirwa kutungamirwa nevashandi vekurapa kuti vave nechokwadi chekurapa kwekurapa uye kuderedza mhedzisiro inogona kuitika.

CarbetutinIs a synthetic oxytoin analog inonyanya kushandiswa kudzivirira postplatum horparthage, kunyanya kutevedzera zvikamu zveCesarea. Postpartum Horrhage icle comlication iyo inogona kuitika mushure mekubereka, kazhinji nekuda kweUterine Atony. CarbetChin Inoshanda nekusunga kweOxytocin Receptings pamusoro peUterine masero emutsara

Kuenzaniswa neyechisikigo oxytocin, Carbetutin ine hupenyu hwakareba-hupenyu, zvinoreva kuti hazviratidzi zvinoshanda mumuviri kwenguva yakareba. Ichi chiitiko chenguva yakareba chinobvumira CarbetCin yekukoshesa kutsigira chibereki chibvumirano, zvichiita kuti chibudirire mukudzivirira postplathag hemorrhage. Pamusoro pezvo, CarbetCocin haidi kuenderera mberi infusion saOxytocin asi inogona kutumirwa seimwe jekiseni, maitiro ekurerutsa kliniki uye kuderedza zvinodiwa pazvinhu zvekurapa.

Zvidzidzo zvekiriniki zvakaratidza kuti Carbetutin zvinobudirira zvakanyanya mukudzivirira kubuda ropa zvichitevera zvikamu zveCesarean, zvakanyanya kuderedza kukosha kwekuwedzera kongotio mishonga yeTherotonic. Sangano reWorld Health Orgorstin (Wakasanganisira CarbetCin seyakarapwa nekudzivirira Postplhage Hemorarhage, kunyanya mune zvigadziriso-zvigadziriso zviripo zvakanakira kutonga kwemutongi mumwechete zvinobatsira zvakanyanya.

Izvo zvakakosha kuti uzive kuti nepo Carbetutin inopa mabhenefiti akakosha mukudzivirira postpartum horparthage, inogona kunge isina kukodzera kune ese mamiriro ezvinhu. Mune zvimwe zviitiko, zvakadai seUttina zvakanyanyisa, kusazvibata zvisina kujairika, kana kubviswa, kumwe kurapa kwekurapa kunogona kuve kwakakodzera. Naizvozvo, kushandiswa kweCarbetCocin kunofanirwa kutsanangurwa nevashandi vane ruzivo rwehutano hwehutano hwakavakirwa pamamiriro ezvinhu chaiwo.

Mukupfupikisa, Carbetutin, seyakareba oxytocin Analog, inotora basa rakakosha mukudzivirira postpartum horparthage hemorrhage zvichitevera zvikamu zviviri zveCesarean uye kuburitswa kwevanhurume. Nekusimudzira chibereki chibvumirano, zvinodzikira njodzi yekubuda ropa kubuda ropa, kuchengetedzwa kwakakosha kwekubereka mwana.

TerlinksinIs jalogict analog yeAndiuretic hormone inonyanya kushandiswa kurapa njodzi dzinokonzerwa neRopa cirrhosis Esophageal vicealal kubuda ropa kwakakura uye kwakasimba mumaronda echirume

Terlinksin inoshanda nekuita chiitiko cheAndiureTETITH HORMONE (Vasopressin) Iyi vasoconstration inobatsira kudzikisa portal vein kumanikidzwa, kuderedza njodzi yekubuda ropa. Kusiyana neSystems Vasopressin, terlinressin ine nguva refu yekuita uye mashoma mhedzisiro, ichiita kuti irambe ichishandiswa zvakanyanya mukuita kwekiriniki.

Pamusoro pekushandiswa kwayo mukushandiswa kwakashata bleeding, terlinressin inoita basa rakakosha mukurapa hepatenerenal syndrome. Hepatorenal syndrome kazhinji inowanzoitika mumatanho epamberi eiyo rwizi rwechiratidzo Terlinessin inogona kuvandudza renal ropa kuyerera, reverse itsvo basa kuderera, uye kugadzirisa zvakanyanya zvabuda murwere.

Izvo zvakakosha kuti uzive kuti nepo terlinress inobudirira kwazvo mukurapa aya mamiriro ekushora, kushandiswa kwaro kunotakura kune dzimwe njodzi, dzakadai sekadzi dzinokanganisa. Naizvozvo, terlinress inowanzopihwa muchipatara muchipatara chiri kutarisirwa nevanyanzvi vehutano nekuchengetedza kuchengeteka uye kushanda kwekurapwa.

Mukupfupikisa, terlinressin, semuchiro wepepu, anoita basa risingaperi mukurapa akabatanidzwa kubuda ropa uye hepatenenal syndrome inokonzerwa nechiropa cirrhosis. Izvo hazvingori chete zvinobudirira kudzora kubuda ropa asiwo kunovandudza basa rekutsamwa, kupa varwere nemikana yakawanda yekuwedzera kurapwa.

BavivalirinIchisheni chePeptide petside inokatyamadzwa seyakananga neThicbbitor Thrombin inoita basa rakaoma muropa rekubatanidza kweropa nekushandura Fibrinogen kuenda kuFibrin, inotungamira ku Thrombus kugadzirwa. Bavalirdudin inoshanda nekubatanidza zvakananga kune iyo inoshanda saiti ye Thrombin, ichivhiringidza chiitiko chacho, nokudaro kuzadzisa zvinokatyamadza.

1. Direct Inhibition ye Thrombin. Ichi chisungo chakanyatsorongeka, chinobvumira bivalirdudin kuti inhibit ese akasununguka mahara thrombin uye thrombin yatove yakasungwa nemavara. Nekuda kweizvozvo, bavesirudin zvinobudirira kudzivirira kuumbwa kwemavara matsva uye kuwedzera kwevaripo.
2. Rapid Onset uye Kudzora. Kuenzaniswa neyakaitika kune indent thatirect Thrbrand Izvi zvinoreva kuti zvayo zvinofungidzirwa zvinofungidzirwa uye zviri nyore kubata, kunyanya mumamiriro ekiriniki anoda kudzora chaiko kwenguva yekubatana, senge picid.
3. Pfupi hafu-hupenyu. Hunhu uhwu hunonyanya kubatsira kune varwere vachida kuti vapfupi asi zvakanyanyisa kurwisa, kwakadai sekutora kwemari yekupindira.
4. Yakaderera kubuda ropa: Nekuda kwezvivakwa zvaro, bavivaldin inopa anticoagation inoshanda neyakadzika njodzi yekubuda ropa. Zvidzidzo zvakaratidza kuti varwere vakabatwa ne bivalirdudin vane huwandu hwakadzika hwekubuda ropa vachienzaniswa neavo vanogamuchira Heparin yakasanganiswa neGP iib / iiia inhibitors. Izvi zvinogadzira bivalirdudin yakachengeteka uye inoshanda anticoaGulant sarudzo muACS uye PCI Varwere.

Mukupfupikisa, bivalirudin, seyakawirwa thrombbbitor, inopa mushonga wakasarudzika wechiitiko uye zvakanakira zvechiriniki. Izvo hazvingori chete zvinobudirira kudzivisa kudzivisa kuumbwa asi kunewo zvakanaka zvakadai sekukurumidza kutanga, hupfupi hafu-hupenyu, uye yakaderera kubuda ropa. Naizvozvo, bavesirudin inoshandiswa zvakanyanya mukurapa kweiyo acutary coronary syndromes uye panguva yekupindira coronary. Nekudaro, kunyangwe yayo yakakwirira yekuchengetedza nhoroondo, inofanira kushandiswa pasi pekutungamirirwa kwehunhu hwehutano hwehutano hwekuita kuti kurapa kuchengetedza uye kushanda.

OctreOdideis a ocapicetic occaptide iyo inotora chiitiko cheStabatin Somatostatin. Somatostatin ndeye hypothalated ne hypothalamus uye mamwe matishu anokanganisa zvakavanzika zvehormone dzakasiyana-siyana, kusanganisira kukura kwehomoni, insulin, glumbual mahormone. Octreotide inoshandiswa zvakanyanya mukuita kwekiriniki kwekurapa kwemamiriro ezvinhu akasiyana-siyana, kunyanya avo vanoda kudzora kwechirongo chehomoni uye zviratidzo zvine hukama.

1. Kurapwa kweAcrogally. OcreTedide inobatsira kudzikisa mazinga ekukura uye insulin , uye kurwadziwa kwakabatana.
2. Kurapa kweCarcinoid Syndrome. OctreETide zvinobudirira kudzora zviratidzo zveCarcinoid syndrome nekunyonganisa chakavanzika cheaya mahormone uye zvinhu zvazvinenge zvichivandudza hupenyu hwevarwere.
3. Kurapwa kwegastroenteropancreattic neurodengacrine tumors (gep-nets). Octreotide inoshandiswa kudzora kukura kweaya ma tumors uye zviratidzo zvavanokonzera, kunyanya mumatauriri anoshanda ayo akavanzika mahormone makuru. Nekurindira mahormone zvakavanzika nemapundu, ocrecodide inogona kuderedza kuitika kwezviratidzo uye, mune zvimwe zviitiko, kukura kwekuputira.
4. Zvimwe Zvikumbiro: Kuwedzera kune yekutanga inoshandiswa inotaurwa pamusoro apa, occreotide inoshandiswa zvakare kurapa dzimwe nguva dzisingawanzo, dzakadai soinulinomas, glucagonomas, uye chipo Uyezve, ocrefude inogona kushandiswa mukurapa kweiyo acute hemorrhagic mamiriro ezvinhu, sekudzora kumusoro kwegastrointestinal kubuda ropa uye Esophageal mutsipa.

Zvakawanda, OctreGide inopa kurapa kunobudirira nekudzivisa zvakavanzika zvehormone dzakasiyana-siyana, kunyanya mukugadzirisa zvirwere nezviratidzo zvine chekuita nehormone secrostion. Nekudaro, sezvo occote inogona kukonzera mamwe mativi, sekusagadzikana kwemamwe matanho, gallstone kugadzirwa, uye shanduko muhuwandu hweropa, kuongorora kweropa uye kurapwa kwekutungamirirwa kwechiremba kunokosha.