Nonapeptide-1 o se tasi o le pa'u pa'epa'e nonapeptide. E mafai ona faʻaaogaina i ituaiga eseese o paʻepaʻe poʻo oloa faʻasaʻo.
Taofi le faʻaogaina o le melanin e ala i le faʻalavelaveina o le gaioiga o le tyrosinase i melanocytes. Faʻaitiitia le hyperpigmentation ma faʻamalamalamaina vaega pogisa na faʻaleagaina e le la ma nisi faʻamaʻi.
Faʻalavelave i le melanocyte stimulating hormone (MSH). E fa'atupula'ia le MSH i le taimi o le ma'itaga, ona o ni tulaga fa'afoma'i fa'apitoa (fa'ata'ita'iga o le ma'i suka, fa'ama'i Addison), ma o se fa'ai'uga o le tele o le la.
Nonapeptide-1, i le maualuga o le 200 ug / mL, e mafai ona taofia atoatoa le faʻaogaina o le melanin i sigi.
I le 100 micromolar concentration, e mafai e le nonapeptide-1 ona taofiofia le 25-35% o gaioiga tyrosinase i faʻataʻitaʻiga manu ma mafai ona faʻaititia le melanin i totonu o melanocytes e 27-43%
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