Nonapeptide-1
Nonapeptide-1 ndi khungu limodzi loyera nonapeptide. Itha kugwiritsidwa ntchito pamitundu yosiyanasiyana ya zoyera kapena zowongolera mawanga.
Imalepheretsa kaphatikizidwe ka melanin mwa kusokoneza zochita za tyrosinase mu melanocytes. Kuchepetsa hyperpigmentation ndi kuunikira mdima madera amene awonongeka ndi dzuwa ndi matenda ena.
Kusokoneza ndi melanocyte stimulating hormone (MSH). MSH imawonjezeka panthawi yomwe ali ndi pakati, chifukwa cha matenda ena (monga matenda a shuga, matenda a Addison), komanso chifukwa cha kutentha kwa dzuwa.
Nonapeptide-1, pamlingo wa 200 ug/mL, imatha kuletsa kwathunthu kaphatikizidwe ka melanin mu bowa.
Pa 100 micromolar concentration, nonapeptide-1 ikhoza kuletsa 25-35% ya zochitika za tyrosinase mu zinyama ndipo imatha kuchepetsa melanin ya melanocytes ndi 27-43%
Kuposa
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