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Monomethylauristatin F (MMAF)
Anarana simika: (S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S) -3-methyl-2-(methylamino)butanamido)fa anamido)-3-methoxy-5-methylheptanoyl)pyrrolidine-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic asidra Lanja molekiola: 731.96 Formula: C39H65N5O8 CAS#: 141205-32-5 Solubility: DMSO hatramin'ny 20 mM Biological Activity Monomethyl auristatin F (MMAF) na desmethyl-auristatin F dia anti-tubulin agent izay manakana ny fizarazarana sela amin'ny fanakanana ny fizarazarana sela. ny tubulin. Izy io dia ... -
Monomethyl Auristatin E (MMAE)
Anarana simika: (S)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2 -yl)amino)-1-methoxy-2-methyl-3-oxopropyl)p yrrolidine-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimethyl-2-(S)-3-methyl-2-(methylamino)butanamido)butanamide Lanja molekiola: 717.98 Formula: C39H67N5O7 CAS: 474645-27-7 Solubility: DMSO hatramin'ny 20 mM Monomethyl Auristatin E dia dolastatin-10 peptide derivative miaraka amin'ny hetsika antimitotika mahery vaika ary mety ho hetsika antineoplastic ho ampahany amin'ny antibody...