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Monomethylauristatin F (MMAF)
Navê Kîmyayî: (S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S) -3-methyl-2-(methylamino)butanamido)lê anamido)-3-metoksi-5-methylheptanoyl)pyrrolidin-2-yl)-3-metoksi-2-methylpropanamido)-3-fenilpropanoic asîd Giraniya molekulî: 731,96 Formula: C39H65N5O8 CAS#: 141205-32-5 Çareserî: DMSO heta 20 mM Çalakiya Biyolojîk Monomethyl auristatin F (MMAF) an desmethyl-auristatin F anjî-tubulîn ajanek e ku ji hêla dabeşkirina hucreyê ve asteng dike. ya tubulin. Ew e ... -
Monomethyl Auristatin E (MMAE)
Navê Kîmyayî: (S)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hîdroksî-1-fenîlpropan-2 -îl)amino)-1-metoksî-2-metîl-3-oksopropil)p yrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimetil-2-((S)-3-methyl-2-(methylamino)butanamido)butanamide Giraniya molekulî: 717.98 Formula: C39H67N5O7 CAS: 474645-27-7 Çareserî: DMSO heta 20 mM Monomethyl Auristatin E peptîdek dolastatin-10 e ku bi çalakiya antimitotîk a bihêz û wekî beşek çalakiya antîneoplastîk a potansiyel e…