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Monomethylauristatin F (MMAF)
Jeneng Kimia: (S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimetil-2-(S) -3-metil-2-(methylamino)butanamido)nanging anamido)-3-metoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-fenilpropanoik asam Bobot molekul: 731.96 Formula: C39H65N5O8 CAS#: 141205-32-5 Kelarutan: DMSO nganti 20 mM Aktivitas Biologi Monomethyl auristatin F (MMAF) utawa desmethyl-auristatin F minangka agen anti-tubulin sing nyegah divisi sel kanthi ngalangi saka tubulin. Iku sawijining ... -
Monomethyl Auristatin E (MMAE)
Jeneng Kimia: (S)-N-((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hidroksi-1-fenilpropan-2 -yl)amino)-1-metoxy-2-methyl-3-oxopropyl)p yrrolidin-1-yl)-3-metoxy-5-methyl-1-oxoheptan-4-yl)-N,3-dimetil-2-(S)-3-methyl-2-(methylamino)butanamido)butanamide Bobot Molekul: 717.98 Formula: C39H67N5O7 CAS: 474645-27-7 Kelarutan: DMSO nganti 20 mM Monomethyl Auristatin E yaiku turunan peptida dolastatin-10 kanthi aktivitas antimitotik kuat lan aktivitas antineoplastik potensial minangka bagéan saka antibodi...