Banirurudinmaka ime

250MG / Vial Ike

Ihe ngosi:BanirurudinA na-egosi maka iji dị ka ọgwụ anticogulant na ndị ọrịa na-arịa ọrịa peronary na-eme ihe (PCI).

Ngwa nke ụlọ ọgwụ: ọ bụ ọgwụ mgbochi incravenous na draịpị.

Ihe ngosi na ojiji

1.1 Nsụgharị Padukary Coroncary (PTCA)

A na-egosi Baburidin maka ịme ihe dị ka ọgwụ mgbochi na ndị ọrịa na-enweghị mgbagha na-enweghị mgbagha na-enwe nsụgharị ike na-agagharị n'ike n'ike n'ike n'ike n'ike (PTCA).

1.2 na ntinye aka (PCI)

Baburudin maka inje na iji Glycoprotein IIB / IIIIA OIIA (GPI) dị ka edepụtara na

A na-egosi ọnwụnwa 2 dị ka anticogulant na ndị ọrịa na-arịa ọrịa peronal / PCI).

A na-egosi Bonirudin maka injection na-egosi maka ndị ọrịa nwere, ma ọ bụ n'ihe ize ndụ nke, Hepain na-etinye ihe na-akpata thrombocytopenia (hittsbosis na-akpata pc.

1.3 US e na aspirin

Baburudin maka injection na Ngosipụta ndị a ezubere maka iji ọgwụ aspirin ma bụrụ naanị ndị ọrịa na-anata ọgwụ aspirin.

1.4 na-eji

Nchedo na ịdị irè nke babudiin maka injection emebebeghị ndị ọrịa na ndị ọrịa nwere nnukwu ọrịa corronary na-agaghị enwe ptca ma ọ bụ PCI.

2 usoro na nchịkwa

2.1 A tụrụ aro dose

Babriarudin maka injection bụ maka nchịkwa enweghị ike.

Baburirun maka injection na-ezubere iji ọgwụ aspirin (300 ruo 325 mg kwa ụbọchị) ma mụọ naanị na ndị ọrịa na-anata ọgwụ aspirin.

Maka ndị ọrịa na-anaghị agba / Hitts

Dose a tụrụ aro nke Base maka injection bụ intravenous (iv) dose nke 0.75 mg / kg / hg / h maka oge PCI / PTCA. A ga-arụ ọrụ minit ise mgbe a ga-arụ ọrụ Bolus, a ga-arụ ọrụ na-arụ ọrụ (na-arụ ọrụ) nke a ga-eme ma ọ bụrụ na a ga-enyekwu boolus 0.3 mg / kg ma ọ bụrụ na achọrọ.

Ekwesịrị ịtụle ndị ọrụ GPI na ihe omume ọ bụla edepụtara na ngbanwe nke edoziri na 2lọta nnwale ahụ dị ugbu a.

Maka ndị ọrịa kụrụ / Hotts

Dose a tụrụ aro nke barvarirun maka injection na ndị ọrịa nwere kụrụ pcpi bụ ihe iv nke 0.75 mg / kg. Ekwesịrị iso na-aga n'ihu na-aga n'ihu na ọnụego 1.75 mg / kg / hg / h ruo oge usoro a.

Maka usoro ọgwụgwọ na-aga n'ihu

A ga-aga n'ihu na-eso PCI / PTCA ruo 4 awa post usoro na ezi uche nke dọkịta.

Na ndị ọrịa nwere nke a na-ahụ maka ihe dị elu myocardial (stemi) na-aga n'ihu na ọnụego infusion ke 1.75 mg / ptca maka ihe ruru 1 awa post crombosis.

Mgbe awa anọ gachara, onye ọzọ na - abanye IV nke IVị maka imerụ ahụ nwere ike ịmalite na ọnụego 0.2 mg / pg / pg dị ala), ọ bụrụ na achọrọ.

2.2 dosing na-enweghị ntụpọ

Enweghi mbelata na bolus dose dị mkpa maka ogo ọrịa gbasara akụrụ. Enwere ike ịdị mkpa ka a belata ya, yana ọnọdụ Anticoulant na-enyocha ndị ọrịa na-enweghị njedebe. Ndị ọrịa nwere ọrịa na-agafeghị oke (30 ruo 59 ml / min) kwesịrị ịnata infusion nke 1.75 mg / kg / hg / hg / hg / hg / hg / hg / hg / hg / hg / hg / hg / hg / hg / hg / hg / hg / hg / hg / hg / hg / hg / hg / hg / hg / hg. Ọ bụrụ na iwepụ creatinine erughị 30 ml / min, mbelata nke ọnụego ka 1 mg / kg / kg / k. Ọ bụrụ na onye ọrịa nọ na hemodialysis, a ga-ebelata ọnụego infusion ka 0.25 mg / kg / h.

Ntụziaka 2.3 maka nchịkwa

Babururun maka injection na-ezubere maka injection Bolus na infusion na-aga n'ihu mgbe idozi ya. Ka ọ bụla 250 mg vial 250, tinye 5 ml nke mmiri na-enweghị atụ maka injection, up. Jiri nwayọ swry ruo mgbe etisasịwo. Na-esote, tụfuo 5 ml site na akpa 50 ml Infusion nwere 5% dextrose na mmiri ma ọ bụ 0.9% sodium chloride maka ogwu. Mgbe ahụ, gbakwunye ọdịnaya nke vial mepere emepe na akpa infuside nwere 5% DEXTROS na mmiri ma ọ bụ 0.9%, 1 ml na 50 ml; 2 vials na 100 ml; 2 vials na 100 ml; 5 vials na 250 ml). Dose ga-edozigharị ya dịka ibu onye ọrịa ahụ (lee Isiokwu 1).

Ọ bụrụ na eji infusion dị ala na-eji mgbe mbụ infusion mbụ gasịrị, akpa itinye uche kwesịrị ịkwadebe. Iji kwadebe ihe a ịta, dozie vial vial vial na 5 ml nke mmiri na-enweghị atụ maka ntụtụ, up. Jiri nwayọ swry ruo mgbe etisasịwo. Na-esote, tụfuo 5 ml site na akpa 500 mil infusion nwere 5% dextrose na mmiri ma ọ bụ 0.9% sodium chloride maka ogwu. Mgbe ahụ, gbakwunye ọdịnaya nke vial mepere emepe na akpa infuside nwere 5% DEXTROS na mmiri ma ọ bụ 0,5 mg / ml. Ọnụego infusion ga-ahọpụta ya site na kọlụm aka nri na tebụl 1.