FAQ

Semaglutideyog glucagon-zoo li peptide-1 (GLP-1) receptor agonist feem ntau siv los tswj cov ntshav qabzib hauv cov neeg mob ntshav qab zib hom 2. GLP-1 yog ib qho endogenous hormone secreted los ntawm L-hlwb nyob rau hauv cov hnyuv me tom qab noj mov, ua si ntau yam physiological luag hauj lwm. Semaglutide ua raws li kev ua haujlwm ntawm lub cev ntawm GLP-1 thiab tswj cov ntshav qabzib thiab qhov hnyav hauv peb txoj hauv kev tseem ceeb:

1. Kev txhawb nqa ntawm Insulin secretion: GLP-1 txhawb kev tso tawm ntawm insulin los ntawm pancreatic β-hlwb thaum cov ntshav qabzib nce siab, pab txo cov ntshav qabzib. Semaglutide txhim kho cov txheej txheem no los ntawm kev ua kom lub GLP-1 receptor, tshwj xeeb tshaj yog ua lub luag haujlwm tseem ceeb hauv kev tswj hwm postprandial hyperglycemia. Cov txheej txheem no ua rau Semaglutide txo qis cov ntshav qabzib tom qab noj mov, txhim kho tag nrho glycemic tswj hauv cov neeg mob ntshav qab zib hom 2.
2. Inhibition ntawm Glucagon secretion: Glucagon yog ib yam tshuaj uas tso tawm los ntawm pancreatic α-cells uas txhawb kev tso cov piam thaj los ntawm lub siab thaum cov ntshav qabzib qis. Txawm li cas los xij, hauv cov neeg mob ntshav qab zib hom 2, glucagon secretion feem ntau nce txawv txav, ua rau cov ntshav qabzib nce siab. Semaglutide inhibits qhov tso tawm ntau dhau ntawm glucagon los ntawm kev ua kom lub GLP-1 receptor, ntxiv pab txo cov ntshav qabzib.
3. Slowing ntawm Gastric Emptying: Semaglutide kuj tseem ua rau lub plab zom mov qeeb, txhais tau hais tias kev nkag mus ntawm cov zaub mov ntawm lub plab mus rau cov hnyuv qeeb qeeb, ua rau cov ntshav qabzib nce zuj zus ntxiv tom qab noj mov. Cov nyhuv no tsis tsuas yog pab tswj cov ntshav qabzib hauv ntshav qab zib nkaus xwb tab sis kuj tseem ua rau muaj kev xav ntawm kev puv, txo tag nrho cov zaub mov noj thiab pab tswj qhov hnyav.

Tshaj li nws cov teebmeem ntawm kev tswj cov ntshav qabzib, Semaglutide tau pom cov txiaj ntsig hnyav hnyav, ua rau nws yog tus neeg sib tw rau kev kho mob rog. Kev poob phaus yog qhov muaj txiaj ntsig tsis yog rau cov neeg mob ntshav qab zib xwb tab sis kuj rau cov neeg tsis muaj ntshav qab zib uas muaj rog.

Cov txheej txheem tshwj xeeb thiab kev kho mob ua tau zoo ntawm Semaglutide ua rau nws yog ib qho tshuaj tseem ceeb hauv kev tswj ntshav qab zib. Tsis tas li ntawd, raws li kev tshawb fawb nce ntxiv, cov kev siv ntawm Semaglutide hauv kev tiv thaiv kab mob plawv thiab kev rog rog tau txais kev saib xyuas. Txawm li cas los xij, qee qhov kev mob tshwm sim, xws li tsis xis nyob hauv plab thiab xeev siab, yuav tshwm sim thaum siv Semaglutide, yog li nws yuav tsum tau siv raws li kev saib xyuas kev kho mob.

Liraglutideyog glucagon-zoo li peptide-1 (GLP-1) receptor agonist feem ntau siv hauv kev kho mob ntshav qab zib hom 2 thiab rog rog. GLP-1 yog cov tshuaj hormones zais los ntawm L-hlwb hauv cov hnyuv me tom qab noj mov, thiab nws ua haujlwm ntau lub luag haujlwm hauv kev tswj cov ntshav qabzib. Liraglutide ua raws li qhov kev txiav txim ntawm GLP-1, ua rau muaj ntau yam tseem ceeb ntawm lub cev:

1. Kev txhawb nqa ntawm Insulin secretion: Thaum cov ntshav qabzib nce siab, GLP-1 txhawb nqa insulin tso tawm los ntawm pancreatic β-hlwb, pab txo cov ntshav qabzib. Liraglutide txhim kho cov txheej txheem no los ntawm kev ua kom lub GLP-1 receptor, tshwj xeeb tshaj yog kev txhim kho cov ntshav qabzib thaum lub sijhawm postprandial hyperglycemia. Qhov no ua rau Liraglutide siv dav hauv kev tswj cov ntshav qabzib tom qab noj mov hauv cov neeg mob ntshav qab zib hom 2.
2. Inhibition ntawm Glucagon secretion: Glucagon yog ib yam tshuaj uas tso tawm los ntawm pancreatic α-cells uas feem ntau txhawb nqa cov piam thaj tso tawm ntawm lub siab thaum cov ntshav qabzib qis. Txawm li cas los xij, hauv cov neeg mob ntshav qab zib hom 2, glucagon secretion feem ntau nce siab, ua rau cov ntshav qabzib siab. Liraglutide pab tswj cov ntshav qabzib los ntawm inhibiting glucagon secretion, txo cov ntshav qabzib hloov pauv hauv cov neeg mob ntshav qab zib.
3. Ua kom lub plab zom mov: Liraglutide kuj ua rau lub plab zom mov qeeb, txhais tau hais tias kev txav ntawm cov zaub mov ntawm lub plab mus rau cov hnyuv qeeb qeeb, ua rau qeeb qeeb ntawm cov ntshav qabzib tom qab noj mov. Cov nyhuv no tsis tsuas yog pab tswj cov ntshav qabzib nkaus xwb tab sis kuj ua rau kom muaj kev xav puv, txo kev noj zaub mov thiab pab cov neeg mob tswj lawv qhov hnyav.
4. Kev tswj qhov hnyav: Ntxiv nrog rau nws cov txiaj ntsig ntawm kev tswj ntshav qabzib, Liraglutide tau pom cov txiaj ntsig hnyav hnyav. Qhov no feem ntau yog vim nws cov teebmeem ntawm kev ua rau lub plab zom mov qeeb thiab nce satiety, ua rau txo cov calories kom tsawg thiab poob phaus. Vim nws qhov ua tau zoo hauv kev txo qhov hnyav, Liraglutide kuj tseem siv los kho cov rog, tshwj xeeb tshaj yog cov neeg mob ntshav qab zib rog rog.
5. Kev tiv thaiv kab mob plawv: Cov kev tshawb fawb tsis ntev los no tau pom tias Liraglutide kuj muaj kev tiv thaiv kab mob plawv, txo cov kev pheej hmoo ntawm cov kab mob plawv. Qhov no tau ua rau nws siv ntau zuj zus rau cov neeg mob ntshav qab zib thiab kab mob plawv.

Hauv cov ntsiab lus, Liraglutide tswj cov ntshav qabzib thiab qhov hnyav los ntawm ntau lub tswv yim, ua lub luag haujlwm tseem ceeb hauv kev tswj ntshav qab zib thiab qhia txog qhov muaj peev xwm hauv kev kho mob rog thiab kev tiv thaiv kab mob plawv. Txawm li cas los xij, qee qhov kev mob tshwm sim, xws li xeev siab, ntuav, thiab hypoglycemia tuaj yeem tshwm sim thaum siv Liraglutide, yog li nws yuav tsum tau siv nyob rau hauv kev saib xyuas kev kho mob kom muaj kev nyab xeeb thiab ua tau zoo.

Tirzepatideyog ib qho tshiab dual-action peptide tshuaj tshwj xeeb uas tsim los rau ib txhij qhib glucagon-zoo li peptide-1 (GLP-1) receptors thiab qabzib-dependent insulinotropic polypeptide (GIP) receptors. Qhov no dual receptor agonism muab Tirzepatide tshwj xeeb kev kho mob zoo hauv kev tswj ntshav qab zib hom 2 thiab tswj qhov hnyav.

1. GLP-1 Receptor Agonism: GLP-1 yog ib qho endogenous hormone secreted los ntawm L-cells nyob rau hauv txoj hnyuv tom qab noj mov, txhawb insulin secretion, inhibiting glucagon tso tawm, thiab ncua lub plab khoob. Tirzepatide txhim kho cov teebmeem no los ntawm kev ua kom GLP-1 receptors, pab txo qis cov piam thaj hauv cov ntshav, tshwj xeeb tshaj yog hauv kev tswj ntshav qabzib tom qab. Tsis tas li ntawd, GLP-1 receptor activation nce satiety, txo cov zaub mov kom tsawg thiab pab kom poob phaus.
2. GIP Receptor Agonism: GIP yog lwm cov tshuaj incretin secreted los ntawm K-hlwb nyob rau hauv txoj hnyuv, txhawb insulin secretion thiab tswj cov roj metabolism. Tirzepatide ntxiv dag zog rau insulin secretion los ntawm activating GIP receptors thiab muaj txiaj ntsig zoo ntawm cov nqaijrog metabolism. Qhov kev ua haujlwm thib ob no ua rau Tirzepatide muaj txiaj ntsig zoo hauv kev txhim kho insulin rhiab heev, txo cov ntshav qabzib, thiab tswj qhov hnyav.
3. Ncua plab plab: Tirzepatide kuj tseem ncua lub plab zom mov, txhais tau hais tias kev txav ntawm cov zaub mov ntawm lub plab mus rau txoj hnyuv me yog qeeb, ua rau cov ntshav qabzib nce zuj zus ntxiv tom qab noj mov. Cov nyhuv no tsis tsuas yog pab tswj cov ntshav qabzib xwb tab sis kuj ua rau kom muaj kev xav puv, ntxiv kom txo tau cov khoom noj.
4. Kev tswj qhov hnyav: Vim nws txoj kev ua kom muaj zog dual ntawm GLP-1 thiab GIP receptors, Tirzepatide tau pom muaj txiaj ntsig zoo hauv kev tswj qhov hnyav. Cov kev tshawb fawb soj ntsuam tau pom tias Tirzepatide tuaj yeem txo lub cev hnyav, tshwj xeeb tshaj yog rau cov neeg mob ntshav qab zib hom 2 uas xav tswj lawv qhov hnyav.

Lub multifaceted mechanism ntawm Tirzepatide muab cov kev xaiv kho tshiab hauv kev tswj cov ntshav qab zib hom 2, tswj cov ntshav qabzib zoo thaum pab cov neeg mob ua tiav qhov hnyav, yog li txhim kho kev noj qab haus huv tag nrho. Txawm hais tias nws cov txiaj ntsig tseem ceeb hauv kev kho mob, qee qhov kev mob tshwm sim, xws li mob plab hnyuv, yuav tshwm sim thaum siv Tirzepatide, yog li nws yuav tsum tau siv raws li kev saib xyuas kev kho mob.

Oxytocinyog ib qho tshwm sim peptide hormone synthesized nyob rau hauv lub hypothalamus thiab khaws cia thiab tso tawm los ntawm lub posterior pituitary caj pas. Nws ua lub luag haujlwm tseem ceeb hauv cov poj niam cev xeeb tub, tshwj xeeb tshaj yog thaum cev xeeb tub thiab lub sijhawm tom qab yug menyuam. Lub luag haujlwm tseem ceeb ntawm Oxytocin yog txhawm rau txhawb nqa cov leeg nqaij hauv plab los ntawm kev khi rau oxytocin receptors ntawm cov leeg nqaij ntawm lub tsev menyuam. Qhov kev ua no yog qhov tseem ceeb rau kev pib thiab tswj cov txheej txheem ntawm kev ua haujlwm.

Thaum lub sij hawm ua hauj lwm, thaum tus me nyuam txav mus los ntawm tus kwj dej yug me nyuam, tso tawm ntawm Oxytocin nce, ua rau muaj zog thiab uterine contractions uas pab xa tus me nyuam. Yog tias qhov kev ua haujlwm ntawm kev ua haujlwm qeeb qeeb lossis nres, cov khoom siv hluavtaws Oxytocin tuaj yeem muab tso rau hauv lub cev los ntawm tus kws kho mob txhawm rau txhim kho uterine contractions thiab ua kom cov txheej txheem ua haujlwm. Cov txheej txheem no hu ua Labor induction.

Ntxiv nrog rau kev txhawb nqa kev ua haujlwm, Oxytocin tau dav siv los tswj kev mob ntshav qab zib tom qab yug menyuam, ib qho teeb meem tshwm sim thiab muaj peev xwm txaus ntshai tom qab yug menyuam. Postpartum hemorrhage feem ntau tshwm sim thaum lub tsev menyuam tsis cog lus zoo tom qab yug menyuam. Los ntawm kev txhim kho uterine contractions, Oxytocin pab txo cov ntshav poob, yog li txo qhov kev pheej hmoo rau leej niam txoj kev noj qab haus huv los ntawm kev los ntshav ntau dhau.

Tsis tas li ntawd, Oxytocin plays lub luag haujlwm tseem ceeb hauv kev pub niam mis. Thaum tus menyuam mos nqus ntawm niam lub txiv mis, Oxytocin raug tso tawm, ua rau cov qog kua mis cog lus thiab thawb cov kua mis los ntawm cov ducts, ua kom cov kua mis tawm. Cov txheej txheem no yog qhov tseem ceeb rau kev pub niam mis zoo, thiab qee zaum Oxytocin yog siv los pab cov niam uas muaj teeb meem thaum lactation.

Zuag qhia tag nrho, Oxytocin yog ib qho tshuaj tseem ceeb hauv kev yug menyuam, nrog rau kev siv dav hauv kev txhawb nqa kev ua haujlwm, tswj ntshav qab zib tom qab yug menyuam, thiab txhawb kev pub niam mis. Thaum Oxytocin feem ntau muaj kev nyab xeeb rau kev siv, nws cov thawj coj yuav tsum tau coj los ntawm cov kws kho mob kom ntseeg tau tias cov txiaj ntsig kho tau zoo thiab txo qis cov kev mob tshwm sim.

Carbetocinyog ib qho hluavtaws oxytocin analog feem ntau siv los tiv thaiv kev mob ntshav qab zib tom qab yug me nyuam, tshwj xeeb tshaj yog tom qab phais tas. Postpartum hemorrhage yog ib qho teeb meem loj uas tuaj yeem tshwm sim tom qab yug me nyuam, feem ntau yog vim uterine atony, qhov twg lub tsev me nyuam tsis cog lus zoo. Carbetocin ua haujlwm los ntawm kev khi rau oxytocin receptors ntawm qhov chaw ntawm lub tsev menyuam cov leeg nqaij pob txha, ua kom cov receptors no, thiab ua rau lub tsev me nyuam contractions, yog li pab txo qis ntshav qab zib.

Piv nrog rau tej yam ntuj tso oxytocin, Carbetocin muaj ib nrab-lub neej ntev, lub ntsiab lus nws tseem active nyob rau hauv lub cev rau ib tug ntev lub sij hawm. Qhov kev ua haujlwm ntev ntev no tso cai rau Carbetocin muab kev sib txuas ntawm lub tsev menyuam, ua rau nws muaj txiaj ntsig zoo hauv kev tiv thaiv ntshav qab zib. Tsis tas li ntawd, Carbetocin tsis tas yuav tsum tau txhaj tshuaj tas li zoo li oxytocin tab sis tuaj yeem siv tau raws li kev txhaj tshuaj ib zaug, ua kom yooj yim cov txheej txheem kho mob thiab txo qhov kev thov ntawm kev kho mob.

Cov kev tshawb fawb soj ntsuam tau pom tias Carbetocin muaj txiaj ntsig zoo hauv kev tiv thaiv los ntshav tom qab phais mob, txo qhov xav tau ntawm cov tshuaj uterotonic ntxiv. Lub Koom Haum Ntiaj Teb Kev Noj Qab Haus Huv (WHO) tau suav nrog Carbetocin ua tus qauv kev kho mob rau kev tiv thaiv kev mob ntshav qab zib tom qab yug me nyuam, tshwj xeeb tshaj yog nyob rau hauv cov chaw muaj kev txwv tsis pub muaj qhov zoo ntawm kev tswj hwm ib koob tshuaj tshwj xeeb tshwj xeeb.

Nws yog ib qho tseem ceeb kom nco ntsoov tias thaum Carbetocin muaj cov txiaj ntsig tseem ceeb hauv kev tiv thaiv ntshav qab zib, nws yuav tsis haum rau txhua qhov xwm txheej. Qee qhov xwm txheej, xws li uterine overdistension, txawv txav placental attachment, lossis detachment, lwm yam kev kho mob yuav tsim nyog dua. Yog li ntawd, kev siv Carbetocin yuav tsum tau txiav txim siab los ntawm cov kws paub txog kev noj qab haus huv raws li cov xwm txheej tshwj xeeb.

Hauv cov ntsiab lus, Carbetocin, raws li kev ua yeeb yam ntev oxytocin analog, ua lub luag haujlwm tseem ceeb hauv kev tiv thaiv kev mob ntshav qab zib tom qab ob qho tib si phais thiab qhov chaw mos. Los ntawm kev txhawb nqa uterine contractions, nws ua tau zoo txo ​​qhov kev pheej hmoo ntawm kev los ntshav tom qab yug me nyuam, muab kev tiv thaiv tseem ceeb rau kev xeeb tub.

Terlipressinyog ib qho hluavtaws analogues ntawm cov tshuaj antidiuretic feem ntau siv los kho cov mob los ntshav los ntawm daim siab mob cirrhosis, xws li esophageal variceal los ntshav thiab hepatorenal syndrome. Esophageal variceal los ntshav yog ib qho teeb meem loj thiab hnyav rau cov neeg mob uas muaj daim siab cirrhosis, thaum hepatorenal syndrome yog ib hom mob raum tsis ua haujlwm uas ua rau lub siab ua haujlwm tsis zoo.

Terlipressin ua haujlwm los ntawm kev ua haujlwm ntawm kev ua haujlwm ntawm cov tshuaj antidiuretic hormone (vasopressin), ua rau cov hlab ntsha ntawm cov hlab ntsha, tshwj xeeb tshaj yog nyob rau hauv txoj hnyuv, yog li txo cov ntshav ntws mus rau hauv lub cev. Qhov no vasoconstriction pab txo qis portal leeg siab, txo qhov kev pheej hmoo ntawm variceal los ntshav. Tsis zoo li cov tshuaj vasopressin ib txwm muaj, Terlipressin muaj lub sijhawm ntev ntawm kev ua haujlwm thiab muaj kev phiv tsawg dua, ua rau nws siv ntau dua hauv kev kho mob.

Ntxiv nrog rau kev siv los ntshav, Terlipressin plays lub luag haujlwm tseem ceeb hauv kev kho mob hepatorenal syndrome. Hepatorenal syndrome feem ntau tshwm sim nyob rau theem siab ntawm daim siab cirrhosis, uas tshwm sim los ntawm kev poob qis hauv lub raum ua haujlwm, nrog rau qhov muaj sia nyob tsawg heev. Terlipressin tuaj yeem txhim kho lub raum cov ntshav khiav, rov qab lub raum ua haujlwm poob qis, thiab txhim kho cov txiaj ntsig ntawm tus neeg mob.

Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias thaum Terlipressin muaj txiaj ntsig zoo hauv kev kho cov mob tseem ceeb no, nws txoj kev siv muaj qee yam kev pheej hmoo, xws li mob plawv. Yog li, Terlipressin feem ntau yog tswj hwm hauv tsev kho mob nyob rau hauv kev saib xyuas zoo los ntawm cov kws kho mob kom ntseeg tau tias muaj kev nyab xeeb thiab ua tau zoo ntawm kev kho mob.

Hauv cov ntsiab lus, Terlipressin, ua cov tshuaj peptide, ua lub luag haujlwm hloov tsis tau hauv kev kho mob los ntshav thiab hepatorenal syndrome tshwm sim los ntawm daim siab cirrhosis. Nws tsis yog tsuas yog tswj tau cov ntshav, tab sis kuj tseem txhim kho lub raum ua haujlwm, muab cov neeg mob muaj sijhawm ntau rau kev kho mob ntxiv.

Bivalirudinyog ib qho tshuaj peptide hluavtaws cais raws li cov thrombin inhibitor ncaj qha, feem ntau yog siv rau kev kho mob anticoagulant, tshwj xeeb tshaj yog nyob rau hauv mob coronary syndromes (ACS) thiab percutaneous coronary intervention (PCI). Thrombin plays lub luag haujlwm tseem ceeb hauv cov txheej txheem ntshav coagulation los ntawm kev hloov fibrinogen rau fibrin, ua rau thrombus tsim. Bivalirudin ua haujlwm los ntawm kev khi ncaj qha mus rau qhov chaw nquag ntawm thrombin, inhibiting nws cov haujlwm, yog li ua tiav cov teebmeem anticoagulant.

1. Direct Inhibition ntawm Thrombin: Bivalirudin khi ncaj qha mus rau qhov chaw nquag ntawm thrombin, thaiv nws kev cuam tshuam nrog fibrinogen. Qhov kev khi no yog qhov tshwj xeeb heev, tso cai rau Bivalirudin los tiv thaiv ob qho tib si dawb thrombin thiab thrombin twb khi rau txhaws. Yog li ntawd, Bivalirudin zoo tiv thaiv kev tsim cov hlab ntsha tshiab thiab txuas ntxiv ntawm cov uas twb muaj lawm.
2. Kev pib nrawm nrawm thiab tswj tau: Bivalirudin muaj qhov pib ua haujlwm sai, sai sai ua cov tshuaj tiv thaiv coagulant raws li kev tswj hwm hauv cov hlab ntsha. Piv nrog rau cov tshuaj indirect thrombin inhibitors (xws li heparin), Bivalirudin qhov kev txiav txim yog ywj siab ntawm antithrombin III thiab muaj kev tswj tau zoo dua. Qhov no txhais tau hais tias nws cov teebmeem anticoagulant muaj kev kwv yees ntau dua thiab tswj tau yooj yim dua, tshwj xeeb tshaj yog nyob rau hauv cov xwm txheej kho mob uas xav tau kev tswj hwm lub sijhawm coagulation, xws li PCI cov txheej txheem.
3. Luv Ib nrab neej: Bivalirudin muaj ib nrab-lub neej luv luv, kwv yees li 25 feeb, tso cai rau nws cov nyhuv anticoagulant kom dissipate sai sai tom qab txiav tawm. Cov yam ntxwv no tshwj xeeb tshaj yog muaj txiaj ntsig zoo rau cov neeg mob uas xav tau luv luv tab sis khaus anticoagulation, xws li thaum cov txheej txheem coronary cuam tshuam.
4. Tsawg los ntshav txaus: Vim nws cov khoom, Bivalirudin muab cov tshuaj tiv thaiv zoo nrog kev pheej hmoo los ntshav. Cov kev tshawb fawb tau pom tias cov neeg mob kho nrog Bivalirudin muaj qhov qis dua ntawm cov teeb meem los ntshav piv rau cov neeg tau txais heparin ua ke nrog GP IIb / IIIa inhibitors. Qhov no ua rau Bivalirudin muaj kev nyab xeeb thiab muaj txiaj ntsig kev xaiv tshuaj tua kab mob hauv cov neeg mob ACS thiab PCI.

Hauv cov ntsiab lus, Bivalirudin, ua ib qho ncaj qha thrombin inhibitor, muaj cov txheej txheem tshwj xeeb ntawm kev ua thiab kev kho mob zoo. Nws tsis tsuas yog ua tau zoo inhibits thrombin los tiv thaiv kev tsim cov ntshav txhaws, tab sis kuj muaj cov txiaj ntsig xws li pib sai, luv ib nrab-lub neej, thiab muaj kev pheej hmoo los ntshav tsawg. Yog li ntawd, Bivalirudin yog dav siv nyob rau hauv kev kho mob ntawm mob coronary syndromes thiab thaum lub sij hawm coronary cuam tshuam. Txawm li cas los xij, txawm tias nws qhov profile muaj kev nyab xeeb siab, nws yuav tsum tau siv raws li kev taw qhia ntawm tus kws kho mob kom ntseeg tau tias kev kho mob muaj kev nyab xeeb thiab ua tau zoo.

Octreotideyog ib qho hluavtaws octapeptide uas ua raws li kev ua ntawm ntuj somatostatin. Somatostatin yog ib yam tshuaj uas tso tawm los ntawm hypothalamus thiab lwm cov ntaub so ntswg uas inhibits kev tso tawm ntawm ntau yam tshuaj hormones, suav nrog kev loj hlob hormone, insulin, glucagon, thiab cov tshuaj hormones digestinal. Octreotide yog siv dav hauv kev kho mob rau kev kho mob ntawm ntau yam mob, tshwj xeeb tshaj yog cov uas yuav tsum tau tswj cov tshuaj hormones secretion thiab qog cov tsos mob.

1. Kev kho mob ntawm AcromegalyAcromegaly yog ib yam mob uas tshwm sim los ntawm kev tso tawm ntau dhau ntawm cov tshuaj hormones loj hlob, feem ntau yog vim muaj pituitary adenoma. Octreotide pab txo qis qib ntawm kev loj hlob hormone thiab insulin-zoo li kev loj hlob factor-1 (IGF-1) nyob rau hauv cov ntshav los ntawm inhibiting lub secretion ntawm kev loj hlob hormone, li no alleviating cov tsos mob ntawm acromegaly, xws li o ntawm tes thiab ko taw, kev hloov nyob rau hauv lub ntsej muag nta. , thiab mob pob qij txha.
2. Kev Kho Mob Carcinoid Syndrome: Carcinoid syndrome yog tshwm sim los ntawm kev tso tawm ntau dhau ntawm serotonin thiab lwm yam khoom siv bioactive los ntawm plab hnyuv carcinoid qog, ua rau cov tsos mob xws li raws plab, dej ntws, thiab kab mob plawv. Octreotide tswj tau cov tsos mob ntawm carcinoid syndrome los ntawm inhibiting qhov tso tawm ntawm cov tshuaj hormones thiab tshuaj, yog li txhim kho lub neej zoo rau cov neeg mob.
3. Kev Kho Mob Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs): GEP-NETs yog ib hom qog nqaij hlav tsawg uas feem ntau tshwm sim hauv plab hnyuv lossis txiav txiav. Octreotide yog siv los tswj kev loj hlob ntawm cov qog no thiab cov tsos mob uas lawv ua, tshwj xeeb tshaj yog nyob rau hauv cov qog ua haujlwm uas zais cov tshuaj hormones ntau. Los ntawm inhibiting cov tshuaj hormones secreted los ntawm cov qog, Octreotide tuaj yeem txo qhov tshwm sim ntawm cov tsos mob thiab, qee zaum, qog hlav qeeb.
4. Lwm Daim Ntawv Thov: Ntxiv rau cov kev siv tseem ceeb uas tau hais los saum toj no, Octreotide kuj tseem siv los kho qee yam kab mob endocrine tsis tshua muaj, xws li insulinomas, glucagonomas, thiab VIPomas (cov qog uas zais vasoactive plab hnyuv peptide). Tsis tas li ntawd, Octreotide tuaj yeem siv rau hauv kev kho mob hemorrhagic mob, xws li tswj lub plab hnyuv los ntshav thiab esophageal variceal los ntshav.

Zuag qhia tag nrho, Octreotide muab kev kho mob zoo los ntawm inhibiting kev tso tawm ntawm ntau yam tshuaj hormones, tshwj xeeb tshaj yog hauv kev tswj cov kab mob thiab cov tsos mob ntsig txog cov tshuaj hormone secretion. Txawm li cas los xij, txij li Octreotide tuaj yeem ua rau qee qhov kev mob tshwm sim, xws li mob plab hnyuv, tsim cov pob zeb, thiab kev hloov pauv hauv cov ntshav qabzib, ua tib zoo saib xyuas thiab kho raws li kev qhia ntawm tus kws kho mob yog qhov tsim nyog.