ac-tyr-thr-ser-leu-ile-his-ser-leu-ile-glu-glu-ser-gln-asn-gln-gln-glu-lys-asn-glu-gln-glu-leu-leu-glu-leu-asp-lys-trp-ala-ser-leu-trp-asn-trp-phe-nh2 acetate salt
fields of application:
human immunodeficiency virus type 1 (hiv-1) infection
enfuviritide is used in combination with other antiretroviral agents in therapy-experienced patients with evidence of hiv-1 replication despite ongoing antiretroviral therapy.
active substance:
enfuvirtide is a 36 amino acid peptide corresponding to a region of gp41, the transmembrane subunit of hiv-1 envelope protein.enfuvitide belongs to the therapeutic class of fusion inhibitors and acts by binding to gp41 and impeding the conformational changes in gp41 necessary for fusion of the virus with the cell.