ʻO ke ʻano molekala:

C76H104N18O19S2

Kaumaha Molecular Pili:

1637.90 g/mol

Helu CAS:

38916-34-6 (ʻupena)

Waihona no ka wā lōʻihi:

-20 ± 5°C

Nā huaʻōlelo like:

Somatostatin-14; SRIF-14;
ʻO ka Somatotropin Release-Inhibiting Factor; SRIF

Kaʻina:

H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH acetate paʻakai (Disulfide bond)

Nā kahua noi:

ʻO ka maʻi maʻi koko
Hemorrhagic gastritis
Ma hope o ka hana ʻana i ka pancreatic a me ka duodenal fistula
ʻO ka hemorrhage variceal

Mea Hana:

ʻO Somatostatin (SRIF) he mea hoʻopaneʻe i ka hoʻokuʻuʻana o ka hormone ulu mai ka pituitary anterior a no laila he mea kū'ē i ka GRF. Somatostatin e kāohi i ka hoʻokuʻuʻana i nāʻano hormones'ē aʻe i komo i ka hoʻoponoponoʻana i nā hana physiological koʻikoʻi o ka'ōpū o ka'ōpū. Hoʻopili pū ʻo Somatostatin i ka hana TSH. ʻO Somatostatin kahi peptide 14-amino acid i kapa ʻia no kona hiki ke kāohi i ka hoʻokuʻu ʻana o ka pituitary GROWTH HORMONE, i kapa ʻia hoʻi ka somatotropin release-inhibiting factor. Hōʻike ʻia ia i loko o nā ʻōnaehana nerve waena a peripheral, ka ʻōpū, a me nā mea ʻē aʻe. Hiki i ka SRIF ke kāohi i ka hoʻokuʻu ʻana o THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; a me GLUCAGON ma waho aʻe o ka hana ʻana ma ke ʻano he neurotransmitter a me neuromodulator. I loko o kekahi mau ʻano me nā kānaka, aia kekahi ʻano somatostatin, SRIF-28 me kahi hoʻonui 14-amino acid ma ka N-terminal.

Moʻolelo Hui: