Faq

SemaglutideGlucagon-kamar peptide-1 (glp-1) mai rikitarwa Augtor da farko ana amfani dashi don sarrafa matakan glucose na jini a cikin marasa lafiya da nau'in ciwon sukari na 2. Glp-1 ingantaccen ƙwararren ƙwayoyin cuta ne a cikin ƙaramin hanji bayan cin abinci, kunna mahara masu yawa na rayuwar kimiya. Semaglutide Mimics Abubuwan da Jiki Likita na Hall-1 kuma suna tsara glucose jini da nauyi a manyan hanyoyi uku:

1. Inganta Insulin: Glp-1 yana ƙarfafa ƙwayar insulin daga sel-ƙwayoyin cuta lokacin da aka haɓaka matakan glucose jini jini, taimaka wajan rage glucose jini. Semaglutide yana haɓaka wannan aikin ta hanyar kunna mai ƙima na Glp-1, musamman yana wasa mai mahimmanci wajen gudanar da rawar da ke haifar da hyperglycemia. Wannan tsarin yana bawa SeMaglutide don rage yawan abinci mai gudana Spikes ya tsayar da glucose na jini da kyau a cikin marasa lafiya mai 2.
2. Harshen Gluckagon Secration: Glucagon wani ganyayyaki ne na pacreatic sel wanda pactreatic α-sel da ke inganta sakin glucose daga hanta lokacin da matakan glucose jini ke ƙasa. Koyaya, a cikin marasa lafiya da nau'in ciwon sukari na 2, asirin Glucagon yana ƙaruwa, yana haifar da matakan glucose na jini. Semaglutide yana hana raunin da ya wuce kibiya ta hanyar kunna mai karbar hoto ta 1, ya kara taimaka ga rage matakan glucose jini.
3. Raunin Gastric Earfafa: Semaglutide kuma yana rage yawan tashe-gaba, ma'ana cewa nassi na abinci daga ciki zuwa karamin hanji ya jinkirta matakan da aka jinkirta a cikin matakan glucose na abinci. Wannan tasirin ba kawai taimaka kula da gurbataccen jini ba amma kuma yana haɓaka jin ƙoshin lafiya, yana rage yawan abinci tare da haɓakawa cikin girman sarrafawa.

Bayan tasirinsa game da tsarin glucose na jini, Semaglutide ya nuna mahimman rashi mai nauyi, ya sa ya zama dan takarar sulhu. Rage nauyi yana da amfani kawai don marasa lafiya masu ciwon sukari amma kuma don mutane masu ciwon sukari da kiba.

Al'amari na musamman na samar da asibiti na Semaglutide sa shi magani mai mahimmanci a cikin ciwon sukari. Bugu da ƙari, a matsayin cigaban bincike, aikace-aikace masu yuwuwa na Semaglutide a cikin kariya na zuciya da magani na kiba suna samun kulawa. Koyaya, wasu sakamako masu illa, kamar rashin jin daɗi da tashin hankali, na iya faruwa yayin amfani da Semaglutide, don haka ya kamata a yi amfani da shi a ƙarƙashin kulawar likita.

LaftaaglutideShaye-glucagon-kamar peptide-1 (glp-1) wanda aka yi amfani da shi a cikin kula da nau'in sukari na 2 da kiba. GLP-1 hormone ne mai zaman kansa da sel a cikin ƙaramin hanji bayan cin abinci, kuma yana taka rawa da yawa wajen tsara glucose na jini. Liraglutide MIMICICS Aikin Aikin GLP-1, yana fuskantar sakamako masu tasiri da yawa:

1. Inganta Insulin: A lokacin da matakan glucose jini jini ya tashi, GLP-1 yana ƙarfafa ɓoye insulin daga sel -roatic β-sel, taimaka wa ƙananan matakan glucose na jini. Laftalutide yana haɓaka wannan aikin ta hanyar kunna mai karɓar Glp-1, musamman inganta ikon glucose na jini a lokacin hasashen sarauta yayin hyperglycemia. Wannan yana sa Lineaglutide da yawa a cikin sarrafa kayan cin abinci na jini a cikin marasa lafiya tare da nau'in ciwon sukari na 2.
2. Harshen Gluckagon Secration: Glucagon wani ganyayyaki ne da aka ɓoye ta hanyar ƙwayoyin pac -reatic wanda yawanci yana inganta glucose sakin glucose daga hanta lokacin da matakan glucose jini ke ƙasa. Koyaya, a cikin marasa lafiya da nau'in ciwon sukari na 2, asirin Glucagon yana da yawa, yana haifar da matakan glucose na jini. Liraglutide yana taimakawa iko da jini na jini ta hanyar inbhibited asirin Glucose, rage yawan glucose jini a cikin masu cutar sankara.
3. Jinkirtar da rashin kwanciyar hankali: Laftaaglutide kuma yana rage yaushe meticing, ma'ana cewa motsi na ciki ya jinkirta matakan cigaban abinci na jini. Wannan tasirin ba kawai cutar ba ne a cikin ikon glucose jini jini amma kuma yana haɓaka jin ƙoshin lafiya, rage zafin abinci da taimaka wa marasa lafiya su sarrafa nauyinsu.
4. Gudanar da GudanarwaBayan tasirinsa akan ikon glucose jini, laftaaglutide ya nuna mahimman asarar nauyi. Wannan shine galibi saboda tasirin sa akan jinkirin rashin kwanciyar hankali da kara bugun zuciya, jagoranta zuwa rage yawan caloric da asara mai nauyi da nauyi. Saboda tasirinsa a rage nauyi, ana amfani da Lafta a cikin maganin kiba, musamman a cikin masu cutar sankara da kiba.
5. Kariyar zuciya: Karatun kwanan nan sun nuna cewa Laftalutide kuma yana da tasirin kariya na zuciya, rage haɗarin abubuwan da suka faru na zuciya. Wannan ya haifar da haɓaka amfani da shi a cikin marasa lafiya tare da ciwon sukari da cutar cututtukan zuciya.

A taƙaice, Laftaaglutide yana tsara glucose jini da nauyi ta hanyar mahimman hanyoyin sarrafawa da kuma nuna yiwuwar jiyya da kariyar zuciya da kariya. Koyaya, wasu sakamako masu illa, kamar tashin zuciya, masu amai, da hypoglycemia, na iya faruwa yayin amfani da Lreaglutide, saboda haka ya kamata a yi amfani da shi a karkashin kulawar Lafiya da tabbatar da aminci da inganci.

TirzeptaideShin sabon abu ne mai ban sha'awa-mataki-mataki pptide da aka tsara don a lokaci guda kunna Glucagon-1 (GLP-1) Masu karɓa da Glucose mai ƙarfin zuciya (gihi) masu karɓa. Wannan agonism na dawo da wannan rikice-rikice yana ba da tirzepatide na musamman na asibiti a cikin sarrafa masu ciwon sukari da nauyi.

1. GLP-1 Mai karɓar AGonism: Glp-1 shine ƙwararrun ƙwayoyin cuta a cikin hanji bayan cin abinci, inganta insulin sakin ciki, da kuma jinkirin yin komai a ciki. Tirzeptade yana inganta wadannan tasirin ta hanyar kunna matakan masu karɓa na 1, taimakawa rage matakan glucose na jini, musamman a cikin tsarin glucose na shemrose. Bugu da ƙari, kunnawa kunnen doki 1 yana haɓaka bugun zuciya, rage zafin abinci da madadin nauyi.
2. Gip mai karɓar tashin hankali: Gibi ne wani wanda K-sel ke ɓoye a cikin hanjin, inganta insulin asirin da kuma daidaita mai. Tirzepta ta kara inganta asirin ta hanyar kunna masu binciken gip kuma yana da tasiri mai kyau kan metabolism na kitse. Wannan tsarin aikin biyu na Dual ya ba Tirzeptaitide mai matukar muhimmanci a inganta tunanin insulin, ya rage matakan glucise na jini, da kuma girman nauyi.
3. Jinkirta rashin kwanciyar hankali: Ma'anar Tirzepatode kuma jinkirin motsin abinci daga ciki zuwa kananan hanjin ya ragu, wanda zai kai ga mafi yawan lokuta na cin abinci na jini. Wannan tasirin ba kawai taimaka kula da glucose na jini ba har ma yana haɓaka jin ƙoshin lafiya, ci gaba da rage yawan abinci.
4. Gudanar da Gudanarwa: Saboda abin da ya sauya na biyu na Glp-1 da Gip masu karɓa, Tirzeptaide ya nuna tasiri sosai a cikin gudanarwa mai nauyi. Karatun asibiti ya nuna cewa Tirzeptaide na iya rage nauyi na jiki, wanda yake da amfani musamman don masu cutar masu guba 2 waɗanda suke buƙatar sarrafa nauyin su.

Tsarin aikin Tirzepatide yana ba da sabon zaɓi na warkewa a cikin nau'in ciwon sukari na 2. Sarrafa shi yadda ya taimaka musu rasa nauyi. Duk da mahimman tasirin asibiti, wasu sakamako masu illa, kamar rashin jin daɗi, kamar yadda ake amfani da shi yayin amfani da Tirzeptaide, saboda haka ya kamata a yi amfani da shi a karkashin kulawa ta likita.

OmyttocinA zahiri yana faruwa ne a zahiri ko adanawa da adana shi kuma an adana shi kuma ta sake shi ta hanyar glandar Pitrous Priuitary. Yana taka muhimmiyar rawa a cikin tsarin haihuwar mace, musamman yayin aiki da lokacin haihuwa. Babban aikin Oxyttocin shine don internarfafa rikicewar tsoka da ɗaure wa masu karɓa na Oxytochin akan sel tsoka tsoka na mahaifa. Wannan aikin yana da mahimmanci don farawa da kuma kula da aikin aiki.

A yayin aiki, kamar yadda jariri ya motsa ta hanyar canal haihuwa, sakin of oxytocin yana ƙaruwa, yana haifar da ƙarfi da kuma rikice-rikicen igiyar ciki da ke taimaka wa ɗan. Idan ci gaba na halitta na aiki ya yi jinkirin ko kuma ya stalled, roba na baya na iya sarrafawa don haɓaka ƙirar igiyar ciki da hanzarta aiwatar da aikin. Wannan hanya ana san shi ne da shigowar aiki.

Baya ga yin aiki da aiki, Oxyttocin an yi amfani da shi sosai don sarrafa badowru na haihuwa, gama gari ne da yiwuwar rikitarwa na bayan haihuwa bayan haihuwa. Kwakwalwar haihuwa na haihuwa ya faru ne lokacin da mahaifa ta kasa yin kwangila ta yadda ya kamata bayan isarwa. Ta hanyar inganta rikicin na ciki, Oxyttocin yana taimakawa rage asarar jini, ta hakan ya rage hadarin ga lafiyar mahaifiyar ta haifar da zub da jini.

Bugu da ƙari, oxytocin taka rawa sosai a cikin shayarwa. Lokacin da wani jariri ya tsotsa a kan nono, oxytocin an saki, yana haifar da glandar madara ta kwangila da tura madara. Wannan tsari yana da mahimmanci don shayar da nono, da kuma oxyttocin wani lokacin ana amfani da su don taimakawa uwaye waɗanda suke fuskantar matsaloli a lokacin lactation.

Gabaɗaya, Oxytocin magunguna ne da ba makawa a cikin boko, tare da aikace-aikacen dazuzzuka a cikin masu aiki, tare da tallafawa ƙwallon ruwa. Yayinda Oxytocin galibi yana da haɗari sosai don amfani, gwamnatinta ya kamata koyaushe ta kasance ta hanyar kwararru na likita don tabbatar da ingantaccen sakamako na warkewa da rage yiwuwar tasirin cutar.

CarbetocinShin analocin oxyttocin analog da farko ana amfani dashi don hana bashin bayan haihuwa, musamman masu bin sassan Cesarean. Rotmarfin bayan bayanwar haifuwa babban rikich ne wanda zai iya faruwa bayan haihuwa, yawanci saboda igiyar ciki a tawali'u, inda mahaifa ta kasa yin kwangila yadda ya kamata. Carbetocin yana aiki da ɗaure wa masu karɓar Oxytocin a farfajiya na Uterine Sells, yana kunna waɗannan masu karɓa, da kuma nuna rashin jituwa na ciki, ta hanyar taimakawa haɓakar rashin jinin jijiyoyin haihuwa.

Idan aka kwatanta da Oxyttocin na halitta, CarbetoCin yana da tsawon rai-rayuwa, ma'ana shi ya kasance yana aiki a cikin jiki don ƙarin tsawan lokaci. Wannan ayyukan da aka tsawaita Carbetocin don samar da ƙarin ƙa'idodin daidaitaccen tsari na ci gaba, yana sa shi tasiri sosai wajen hana haifuwa basur. Bugu da ƙari, Carbetocin baya buƙatar ci gaba da jiko kamar oxytocin amma ana iya sarrafa shi azaman allura guda, sauƙaƙe hanyoyin asibiti da rage buƙata a kan kayan aikin likita.

Karatun asibiti ya nuna cewa CarbetoCin yana da tasiri sosai wajen hana zub da jini mai biyo bayan sassan Cesarean, yana rage buƙatar ƙarin magungunan eretonic magunguna. Hukumar Lafiya ta Duniya (wanda) ya hada Carbetocin a matsayin daidaitaccen magani don hana saitunan da ba a san shi ba, musamman a tsayayyen saiti na kayan aiki inda amfanin gwamnatin guda ɗaya yake da amfani sosai.

Yana da mahimmanci a lura cewa yayin carbetocin yana ba da fa'idodi masu mahimmanci don hana batarwar haifuwa, bazai dace da kowane yanayi ba. A wasu yanayi, kamar hadadden igiyar ciki, wanda aka makala mai ɗorewa, ko droachment, matakan magani na iya zama mafi dacewa. Sabili da haka, ana iya yin amfani da carbetocin da ƙwararrun masana kiwon lafiya dangane da takamaiman yanayi.

A taƙaice, Carbetocin, a matsayina mai dadewa Analog, yana taka muhimmiyar rawa wajen hana sassan Cesarean da isar da farjinsu. Ta hanyar inganta rikicin igiyar ciki, yana da kyau yana rage haɗarin zubar jini na jin jinya, yana ba da kariya ga ciwon haihuwa.

TerliprasinTsarin roba ne na antidiuretic Hormone da aka samu wanda ya sa ya haifar da Cirrhos hanta, kamar cututtukan esopathagual na jini da hepatorenal. Rashin Ingancin ESophageal jini ya zama ruwan dare gama gari kuma mai tsananin wahala a cikin cututtukan hanta, yayin da Hepatorenal Syndromise ne na hanjin hanjin hanta.

Terlipressin yana aiki ta hanyar kwaikwayon aikin antidiuric Hormone (Vasopressin), yana haifar da maƙarƙashiya na vectory, musamman a cikin gastrointestinal fili, don haka ya rage jini kwarara zuwa waɗannan gabobin. Wannan vasoconstriction na taimaka wajan rage matsin lamba na vein, rage haɗarin zubar jini. Ba kamar vassipressin vassipressin ba, Terlipresin yana da tsawon lokacin aiki da ƙarancin sakamako, yana sa shi ya zama da yawa a cikin aikin asibiti.

Baya ga amfani a cikin zubar da jini m, terliprasin yana taka muhimmiyar rawa wajen magance cututtukan hepatorenal. Hepatireenal Syndrome yana faruwa a cikin manyan matakai na hanta na hanta, wanda aka kwatanta shi da saurin raguwa a cikin aikin koda, tare da ƙimar rayuwa. Terlipresin na iya inganta kwarwar jini na jini, aikin hana koda koda na koda yana haɓaka sakamako mai haƙuri.

Yana da mahimmanci a lura cewa yayin da Terlipressin yana da inganci sosai wajen kula da waɗannan mahimman yanayi, amfanin sa yana ɗaukar wasu haɗari, kamar tasirin zuciya. Saboda haka, ana amfani da Terlipritsin a cikin wani shirin asibiti a karkashin kwararrun masana ta kulla yarjejeniya da ingancin magani.

A taƙaitaccen, Terlipressin, a matsayin peptipprisin, yana kunna rawar da ba za a iya ba za'a iya ba da shi wajen magance ta hanta. Ba wai kawai yana sarrafa zub da jini ba amma kuma yana inganta aikin koda, yana ba da marasa lafiya tare da ƙarin dama don ƙarin damar don ƙarin jiyya.

BivalirfenShin wani fata ne mai ban sha'awa na roba a matsayin mai ɗaukar hoto na kai tsaye, da farko ana amfani da shi don maganin rigakafi, musamman a cikin cututtukan zuciya mai zurfi (PCI). Thrombin yana taka muhimmiyar rawa a cikin tsarin zubar da jini ta hanyar sauya Fibronogen zuwa fibrin, yana haifar da samuwar Therombus. Ba'idodin Bivenirudin ta hanyar daurin kai tsaye zuwa wurin da ke aiki na Thrombin, suna hanawa aikin sa, don haka cimma sakamako na rigakafin.

1. Kai tsaye hana thrombin: Balbirudin ya ɗaure kai tsaye zuwa cibiyar da ke aiki mai aiki kai tsaye, yana toshe ma'amala da Fibrinogen. Wannan ɗaure hoto ce musamman, kyale Bhivaruudin don hana rago-shiryen Supombin da Thrombin da aka riga aka ɗaure su. A sakamakon haka, Ba'alirudin da kyau ya hana samuwar sabbin hanyoyin da kuma fadada wadanda ake dasu.
2. Saurin kunne da tsari: Ba'alirudin yana da saurin aiki, da sauri samar da tasirin rigakafi akan aikin gwamnati. Idan aka kwatanta da na gargajiyar Thrombint na gargajiya (kamar heparin), aikin Ba'isirin) mai zaman kansa ne na antithrombin III da kuma bayar da mafi kyawun tsari. Wannan yana nufin tasirin antiicoagulant sakamakon da ake iya faɗi kuma mafi sauƙin sarrafawa, musamman a yanayin yanayi na buƙatar madaidaicin iko na lokacin coagular.
3. Gajere rabin rayuwa: Ba'anci yana da ɗan gajeren rayuwa rabin rayuwa, kimanin minti 25, bada izinin tasirin anticiagulant da sauri bayan dakatar. Wannan halayyar tana da fa'ida ga marasa lafiya na buƙatar gajere amma turɓanci, kamar a lokacin aikin ibada na jijiya.
4. Low hadarin zub da jini: Saboda kaddarorinta, da bivirudin yana samar da ingantacciyar maganin anticoar tare da ƙananan haɗarin zubar jini. Nazari ya nuna cewa marasa lafiyar da aka bi da rikice-rikicen jini idan aka kwatanta da waɗanda ke karɓar Heparin da aka karɓa tare da GP IIB / iiia masu hana. Wannan ya sa Ba'alirudin amintaccen da ingantaccen zaɓi na rigakafi a cikin ACs da kuma PCI marasa lafiya.

A takaice, Ba'alirudin, a matsayin mai gabatar da tsaka-tsalle na kai tsaye, yana ba da na musamman tsarin aiki da fa'idodin asibiti. Ba wai kawai yana hana Thrombin don hana samuwar Clot ba amma kuma yana da fa'idodi kamar hadari mai sauri, gajeriyar rabin jini. Saboda haka, balalirudin ana amfani dashi a cikin maganin m jijiyoyin zuciya da kuma lokacin tsaftacewar jijiyoyi. Koyaya, duk da babban amincin aminci, ya kamata a yi amfani dashi a karkashin jagorancin ƙwararren masani don tabbatar da amincin lafiya da inganci.

Octreotideshine octaptide na distapeptide wanda ke kwaikwayon aikin Samfur na zahiri. Samfuron Samfur. Ocreotide ana amfani dashi sosai a aikace na asibiti don kula da yanayi daban-daban, musamman ma ikon sarrafa ƙwararrun ƙwaƙwalwar ƙwaƙwalwa da alamun ƙwayar cuta.

1. Lura da Acromogaly: Acromogaly wani yanayi ne wanda ya haifar da raunin da ya wuce gona da iri, yawanci saboda adeneoma mai girma. Optreotide yana taimaka rage ƙananan matakan haɓakar haɓakawa da insulin-1 (IGF-1) a cikin jini ta hanyar faɗakarwar hannaye, kamar faɗaɗawa da ƙayyadaddun fasali , da hadin gwiwa.
2. Search na Carcinoid Syndrome: Carcinoid Syndrome yana haifar da ɓoyayyen ɓoyayyen herotonin da sauran abubuwa masu yawa ta ciwace-ciwacen cututtukan zuciya, suna haifar da bayyanar cututtuka, flushing, da zuciya. Ocreotide yana sarrafa alamun cututtukan carcinoid wanda aka ba da asirin waɗannan ƙwayoyin cuta da abubuwa, ta haka inganta ingancin rayuwa ga marasa lafiya.
3. Lura da gastroenteropancann neurinenencrine ciwan jini (Gep-nets): Nets-raga wani abu ne mai wuya irin kumburi wanda yawanci yana samo asali ne a cikin gastroases. Ana amfani da octreotide don sarrafa haɓakar waɗannan ciwanmu da alamun bayyanar suna haifar, musamman a cikin ciwace-ciwacen aiki waɗanda keɓaɓɓiyar ƙwayoyin cuta masu yawa. Ta hanyar hana hormunes da ciwan, Octreotide na iya rage abin da ya faru na bayyanar cututtuka kuma, a wasu yanayi, m girma.
4. Sauran aikace-aikacen: Baya ga firam ɗin da aka ambata a sama, kuma ana amfani da Octreotide don magance wasu rikice-rikice na endocrine, kamar su insulinomas, da vipomas cewa sirrin kayan ciki na ciki na ciki). Bugu da ƙari, ana iya amfani da Octreotide a cikin maganin cututtukan ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ciki

Gabaɗaya, Octreotide yana ba da ingantaccen magani ta hanyar hanzarta raunin kwayoyin halitta, musamman a cikin kamuwa da cututtuka da alamu masu alaƙa da ƙurjin. Koyaya, tunda octreotide na iya haifar da wasu illa, kamar rashin jin daɗi na gastrointestal na jini, da canje-canje a cikin jagorancin glucose jini, kulawa da kulawa da magani a ƙarƙashin jagorancin likita ya zama dole.