1ml: 4μg / 1ml: 15μg Ƙarfi

Nuni:

ALAMOMIN DA AMFANI

Hemophilia A: Desmopress a cikin Acetate Injection 4 mcg / mL an nuna ga marasa lafiya tare da hemophilia A tare da factor VIII coagulant ayyuka matakan fiye da 5%.

Desmopress a cikin allurar acetate sau da yawa yana kula da hemostasis a cikin marasa lafiya tare da hemophilia A yayin ayyukan tiyata da kuma bayan tiyata lokacin da aka gudanar da mintuna 30 kafin tsarin da aka tsara.

Desmopress a cikin allurar acetate kuma zai dakatar da zubar jini a cikin hemophilia A marasa lafiya tare da raunin da ba a so ko raunin da ya faru kamar su hemarthroses, hematomas na intramuscular ko zubar da jini na mucosal.

Desmopress a cikin allurar acetate ba a nuna don maganin hemophilia A tare da matakan VIII coagulant matakan daidai da ko ƙasa da 5%, ko don maganin hemophilia B, ko a cikin marasa lafiya waɗanda ke da ƙwayoyin cuta na factor VIII.

A wasu yanayi na asibiti, yana iya zama barata don gwada desmopress a cikin allurar acetate a cikin marasa lafiya tare da matakan factor VIII tsakanin 2% zuwa 5%; duk da haka, ya kamata a kula da waɗannan marasa lafiya a hankali. von Willebrand's Disease (Nau'in I): Ana nuna Desmopres s a cikin allurar acetate 4 mcg / ml ga marasa lafiya tare da cutar von Willebrand mai sauƙi zuwa matsakaici (Nau'in I) tare da matakan factor VIII fiye da 5%. Desmopress a cikin allurar acetate sau da yawa yana kula da hemostasis a cikin marasa lafiya tare da cutar von Willebrand mai sauƙi zuwa matsakaici yayin hanyoyin tiyata da kuma bayan tiyata lokacin da aka gudanar da mintuna 30 kafin tsarin da aka tsara.

Desmopress a cikin allurar acetate yawanci zai dakatar da zub da jini a cikin sauƙi zuwa matsakaicin marasa lafiya na von Willebrand tare da raunin da ba zato ba tsammani ko raunin da ya faru kamar hemarthroses, hematomas na intramuscular ko zubar jini na mucosal.

Wadancan marasa lafiya na cutar von Willebrand waɗanda ba su da yuwuwar amsawa su ne waɗanda ke da cutar homozygous von Willebrand mai tsanani tare da factor VIII coagulant aiki da factor VIII von

Willebrand factor antigen matakan kasa da 1%. Sauran marasa lafiya na iya ba da amsa ta yanayi daban-daban dangane da nau'in lahani na kwayoyin da suke da shi. Lokacin zubar da jini da factor VIII coagulant aiki, ristocetin cofactor aiki, da von Willebrand factor antigen ya kamata a duba a lokacin gudanar da desmopress a cikin allurar acetate don tabbatar da cewa ana samun isasshen matakan.

Desmopress a cikin allurar acetate ba a nuna shi ba don maganin cutar von Willebrand mai tsanani (Nau'in I) da kuma lokacin da aka sami shaidar wani nau'i na kwayoyin halitta mara kyau na factor VIII antigen.

Ciwon sukari Insipidus: An nuna Desmopress a cikin allurar acetate 4 mcg / ml a matsayin maganin maye gurbin maganin antidiuretic a cikin kulawa da insipidus na tsakiya (cranial) ciwon sukari da kuma kula da polyuria na wucin gadi da polydipsia bayan ciwon kai ko tiyata a cikin yankin pituitary.

Desmopress a cikin allurar acetate ba shi da tasiri don kula da ciwon sukari na nephrogenic insipidus.

Desmopress a cikin acetate kuma yana samuwa azaman shiri na intranasal. Duk da haka, wannan hanyar isar da isar da sako na iya lalacewa ta hanyoyi daban-daban waɗanda za su iya sa kumburin hanci ba shi da tasiri ko kuma bai dace ba.

Wadannan sun hada da rashin sha na ciki, cunkoson hanci da toshewa, fitar da hanci, zubar da hancin hanci, da kuma rhinitis mai tsanani. Isar da ciki na iya zama bai dace ba inda aka sami rashin fahimta. Bugu da ƙari, hanyoyin tiyata na cranial, irin su transsphenoidal hypophysectomy, suna haifar da yanayi inda ake buƙatar madadin hanyar gudanarwa kamar a lokuta na tattara hanci ko farfadowa daga tiyata.

RASHIN HANKALI

Desmopress a cikin allurar acetate 4 mcg / mL an hana shi a cikin mutane tare da sanannen hypersensitivity zuwa desmopress a cikin acetate ko kowane ɗayan abubuwan desmopress a cikin allurar acetate 4 mcg / mL.

Desmopress a cikin allurar acetate an hana shi a cikin marasa lafiya tare da matsananciyar rauni na koda (wanda aka ayyana azaman izinin creatinine a ƙasa 50ml/min).

Desmopress a cikin allurar acetate an hana shi a cikin marasa lafiya tare da hyponatremia ko tarihin hyponatremia.