As of December 31, 2018, we had cash and cash equivalents of approximately $24.2 million, short-term deposits of approximately $6.0 million and marketable debt securities of approximately $60.0 million invested in accordance with our investment policy, totaling approximately $90.2 in highly-liquid assets, as compared to cash and cash equivalents of approximately $13.0 million and marketable debt securities of approximately $6.0 million invested in accordance with our investment policy, totaling approximately $19.0 in highly-liquid assets as of December 31, 2017. The increase is mainly attributable to the approximately $70.3 million in net proceeds raised in an underwritten public offering that was completed in June 2018, together with $5.9 million in net proceeds raised in a registered direct offering during April 2018.

The 2013 Plan is administered by our Board, which, on its own or upon the recommendation of our remuneration committee or any other similar committee of the Board, shall determine, subject to applicable law, the identity of grantees of awards and various terms of the grant. Consistent with our Compensation Policy, the 2013 Plan provides for granting options to purchase our ordinary shares pursuant to Section 102 of the Israeli Income Tax Ordinance, or the Ordinance, under the capital gains route, to directors, officers and employees who are Israeli residents holding (or have a right to hold or to purchase) less than 10% of our total share capital and do not have a right to receive 10% or more of the Company’s profits.

Hi Paul, In regard to walking speed in old people. If walk slower than 1.8 mph decreased survival. My guess if live in NYC and walk slower than 1.8 mph you are going to road kill when try to cross the street. On other hand if walk faster than 2.3 mph good chance can make across the street.

As of December 31, 2018, the Company had approximately $63.9 million net-operating-loss carry forwards, consisting of approximately $12.0 million of Maltese net-operating-loss carry forwards and approximately 51.9 million Israeli net-operating-loss carry forward. Additionally, the Company had approximately $1.2 million of capital loss carry forward from the sale of marketable debt securities. The Maltese and the Israeli loss carry forwards have no expiration date.

Dubey, A. K., Basu, B. & Bandyopadhyay, A. Pulsed electrical stimulation and surface charge induced cell growth on multistage spark plasma sintered hydroxyapatite-barium titanate piezobiocomposite. J. Am. Chem. Soc. 97, 481–489 (2014).

Approximately 1 × 106 cells were treated with serum-depleted medium (0.1% FBS) for 24 h to synchronize growth. Then cells were incubated in complete culture medium for another 24 h, detached by trypsinization, stored in culture medium and recovered by centrifugation. After fixation with 75% ethanol overnight at 4 °C, cells were digested with DNase-free RNase in PBS containing 5 μg/ml propidium iodide (PI) for DNA staining (30 min at 37 °C). FACS analysis was performed using a BD FACS Calibur flow cytometer equipped with CELL Quest software.

To the individual who got breast cancer after 4 years of losartan. Cancer usually occurs about 20 years after exposure (it’s called “latency”). Extremely high doses can cause it to happen more quickly, but the issue with drugs regards very low levels. Cancer within 4 years is not likely.

We may experience rapid and substantial growth in order to achieve our operating plans, which will place a strain on our human and capital resources. Successful implementation of our business plan will require management of growth, which will result in an increase in the level of responsibility for management personnel. Although we have a relatively small number of employees, as we prepare for the ARMOR Study we have been increasing our operations, including expanding our employee base of managerial, operational, clinical and financial personnel. Any future growth will impose significant added responsibilities on members of management, including the need to identify, recruit, maintain and integrate additional employees. To that end, we must be able to, among other things:

Dividends distributed by a Preferred Technology Enterprise or a Special Preferred Technology Enterprise, paid out of Preferred Technology Income, are subject to withholding tax at source at the rate of 20%, or such lower rate as may be provided in an applicable tax treaty (subject to the receipt in advance of a valid certificate from the Israel Tax Authority allowing for a reduced tax rate). However, if such dividends are paid to an Israeli company, no tax is required to be withheld. If such dividends are distributed to a foreign parent company holding at least 90% of the shares of the distributing company and other conditions are met, the withholding tax rate will be 4% (or a lower rate under a tax treaty, if applicable, subject to the receipt in advance of a valid certificate from the ITA allowing for a reduced tax rate).

That is a very interesting study you just posed, do you think metformins interference with mitochondrial complex 1 woud fall into the category of “mild stess”?

ASI Technology Corp. (OTCBB:ASIT) specializes in the development of advanced patented plasma technologies. ASI staff has extensive experience in the disciplines of science, physics and engineering with a focus on advanced plasma physics. ASI has innovated, developed and patented new applications of plasma in the areas of decontamination and sterilization, antennas, communication links, electronic shielding and noise reduction. The Company has worked on plasma projects with General Dynamics, University of Tennessee, the U.S. Missile Defense Agency, the U.S. Navy, the U.S. Air Force, University of Mississippi and Malibu Research, Inc. The Company is currently focused on validating its cold plasma decontamination and sterilization method and developing prototypes. The Company also makes short-term investment loans for income to support operations.

The consolidated financial statements have been prepared in accordance with United States Generally Accepted Accounting Principles ("U.S. GAAP").