If we encounter difficulties enrolling patients in our clinical trials, our clinical development activities could be delayed or otherwise adversely affected.

        Should our obligation under an indemnification provision exceed applicable insurance coverage or if we were denied insurance coverage, our business, financial condition and results of operations could be adversely affected. Similarly, if we are relying on a collaborator to indemnify us and the collaborator is denied insurance coverage or the indemnification obligation exceeds the applicable insurance coverage and does not have other assets available to indemnify us, our business, financial condition and results of operations could be adversely affected.

To me, the 2012 Blasco study looks very interesting. However, I am not familiar with gene therapy so I am more in a learning mode here. Of particular interest, multiple measures of aging improved in the 2 mTERT groups compare to the other groups (control and eGFP group): decreased p16 levels, decreased short telomeres, increased bone density, decreased insulin levels,…). Life span increase was significant in both 1y and 2y groups.

These financial statements are the responsibility of the Company’s management. Our responsibility is to express an opinion on the Company’s financial statements based on our audits. We are a public accounting firm registered with the Public Company Accounting Oversight Board (United States) (PCAOB) and are required to be independent with respect to the Company in accordance with the U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.

Our ordinary shares that are fully paid for are issued in registered form and may be freely transferred under our Articles, unless the transfer is restricted or prohibited by applicable law or the rules of a stock exchange on which the shares are traded. The ownership or voting of our ordinary shares by non-residents of Israel is not restricted in any way by our Articles or the laws of the State of Israel, except for ownership by nationals of some countries that are, or have been, declared as enemies of Israel.

Licensing revenue amounted to $1.1 million during the year ended December 31, 2017, compared to $0.5 million of revenue for the year ended December 31, 2016. The above-mentioned revenue resulted from the amortization of the upfront payments under the Samil Agreement.

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I agree that he needs to work with a cardiologist, to identify location and type of arrhythmia, but a cardiologist that is open and friendly to nutritional supplements.

arrangements, and claims involving healthcare items or services reimbursed by non-governmental third-party payors, and are generally broad and are enforced by many different foreign and state agencies as well as through private actions. Some state laws require pharmaceutical companies to comply with the pharmaceutical industry’s voluntary compliance guidelines and the relevant compliance guidance promulgated by the federal government and require drug manufacturers to report information related to payments and other transfers of value to physicians and other healthcare providers or marketing expenditures. State and foreign laws also govern the privacy and security of health information in some circumstances, many of which differ from each other in significant ways and often are not pre-empted by HIPAA, thus complicating compliance efforts.

(A) P311 expression and distribution in kidney tissues after sham-operation (Sham) or unilateral ureteral obstruction (UUO) in adult mice, as evidenced by immunohistochemistry. Black arrowhead indicates the P311-positive region. P311-positive region was quantified in stained sections from the Sham (n = 6) and UUO (n = 6) groups. Data are presented as the mean ± SD. *P < 0.05; **P < 0.01. (B) TGFβ1 and α-SMA as well as acidophilic degeneration seem to be co-localized with P311 in some tubular epithelial cells within serial sections from mouse obstructed kidneys (n = 6). (a) Hematoxylin and eosin staining of mouse renal fibrosis samples (n = 6). Black arrowhead indicates acidophilic degeneration. (b) P311 immunoreactivity in the cytoplasm of some tubular epithelial cells from mouse renal fibrosis samples (n = 6). Black arrowhead indicates the P311-positive region. (c) α-SMA immunoreactivity in the cytoplasm of some tubular epithelial cells from mouse renal fibrosis samples (n = 6). Black arrowhead indicates the α-SMA-positive region. (d) TGFβ1 immunoreactivity in the cytoplasm of some tubular epithelial cells from mouse renal fibrosis samples (n = 6). Black arrowhead indicates the TGFβ1-positive region. (e) Negative control for the immunohistochemical staining on mouse renal fibrosis samples (n = 6). (A,B) are representative of at least three similar experiments. Scale bar: 100μm.

For the Russians, the most important player in the room was probably the Chinese. President Xi attended the EEF for the very first time. He brought to the table a slew of treaties and agreements related to commerce, trade, and people-to-people and cultural exchanges. The Chinese and the Russians have never been so close than now, at least in terms of imageries, symbolisms and perceptions. Both of them have closely aligned objectives, including the wish to see a multipolar world instead of a unipolar one and the need to manage tensions with the West.

Regarding IF, in addition to the many health benefits that you have mentioned, do we have also data showing significant life span extension in animal models?