Ainm ceimigeach:(Ean) -2 - ((2R, 3r) -3 - ((((((3mh, 5-Dimhethyl-2 - ((S) -3-methyl-2- (methylamino) putanaido) ach anamido) -3-methyleoyloyl) pyrridin-2-yl) -3-methylpropanai) -3-thonylpropano searbhag

Cuideam Molecular:731.96
Foirmle:C39H65n5no8
Cas #:141205-32-5
Solubility:DMSO suas gu 20 mm

Gnìomhachd bith-eòlasach
Tha Monomethyl Auristatin F (MMAF) no dìcheallach-auristatin f na neach-ionaid anti-tubalin le bhith a 'cur bacadh air pooldization of tubulin. Tha e ùrAuristatin derivativele phasganan c-chrìochnachaidh C -omhimhean a tha a 'cur a chur an gnìomh cytotoxic an coimeas ris an co-obrachadh neo-chunbhalach, Monomeyl Auristatin E (MMAE). A bharrachd air an sin, chan eil ach aig a 'bhuidheann Amino N-terminal achaonwoothyl wallitauet an àite dhà a-staighAuristatin ffhèin.