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Linaclyide
Prìomh fhaclan
- LinaclyideBunait
- A 'phrìs as ruigsinneach
- Cas # 851199-59-2
Mion-fhiosrachadh luath
- PLOENS:Linaclyide
- Casno: 851199-59-2
- Foirmle molecular: c59H79N15O21S6
- Coltas: pùdar geal
- Iarrtas: Air a chleachdadh airson casg ciùird
- Ùine lìbhrigidh: Luing sgiobalta
- Pasgan: A rèir riatanasan neach-ceannach
- Port: Shenzhen
- Cinneasachadh: 1 cileagram / mìos
- Purity: 98%
- Stòradh: 2 ~ 8 ℃. air a dhìon bho sholas
- Còmhdhail: Le Air
- Cuingealaich: 1 gram
Superiority
Mion-fhiosrachadh
Bathar: Linecatilide
Co-fhacal: linaclachide acetate
Cas Àireamh: 851199-59-2-2
Foirmle molecular: c59H79N15O21S6
Cuideam Molecular: 1526.8
Coltas: pùdar geal
Purity:> 98%
Seichence: NH2-CYS-CYS-CYL-CYL-CYL-Pro-ala-Pro-gu-sgeul-air-gull-Try-Gly-Cyr-Gly-cyr-sur-oh
Tha LineCallide na chuingeal-cinneach agus Agonn Cyclash Insyne C (GC-C), a tha càirdeach do Structar Gaincely C (a tha càirdeach do theaghlach Petylide guanylin, le gnìomhan neach-reic, analgesic agus leisgeil. Nuair a tha e air rianachd beòil, ceangail linclachain gu agus a 'gnìomhachadh gabhadan GC-C a' lorg air uachdar solais an epithelium intestinal. Tha seo a 'meudachadh dùmhlachd de chlaonadh Intracellular Altracellululara Moneophote (CGMP), a tha a' tighinn bho Thisshosphate Guanoshate (GTP). Bidh CGMP a 'gnìomhachadh Riaghladair eacations eadar-ghluasaich cystic fibrois (CFR) agus a' brosnachadh còtation cloride agus baicabonate a-steach don lumen intestinal. Tha seo a 'brosnachadh sodium topadh a-steach do luchd-lumachd agus a' leantainn gu barrachd dìomhaireachd fluid interstinal. Bidh an seo a 'luathachadh seo aig a' cheann thall gluasad susbaint intestinal, a 'leasachadh gluasad lobh-bhroinn agus a' faochadh casg. Faodaidh barrachd ìrean CGM a thoirt a-machas a thoirt a-mach à bith-a-mach buaidh aninocicepictive, troimhe gu àm fhathast gun a bhith a 'gabhail a-steach tuigse de neo-thoraidhean air fibrichean de fhiodh. Tha linaclyide air a ghlacadh gu beag bhon t-slighe GI.
