Factory best selling Protirelin Gmp Exporter From China - Linaclotide – JYMed
Factory best selling Protirelin Gmp Exporter From China - Linaclotide – JYMed Detail:
Keywords
- Linaclotide Base
- most affordable price
- CAS# 851199-59-2
Quick Details
- ProName: Linaclotide
- CasNo: 851199-59-2
- Molecular Formula: C59H79N15O21S6
- Appearance: white powder
- Application: used for Curing constipation
- DeliveryTime: prompt shipment
- PackAge: according to customer’s requirements
- Port: Shenzhen
- ProductionCapacity: 1 Kilogram/Month
- Purity: 98%
- Storage: 2~8℃. protected from light
- Transportation: by air
- LimitNum: 1 Gram
Superiority
Details
Product: Linaclotide
Synonym: Linaclotide Acetate
CAS No. : 851199-59-2
Molecular Formula: C59H79N15O21S6
Molecular Weight: 1526.8
Appearance: White powder
Purity: >98%
Sequence: NH2-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH
Linaclotide is a synthetic, fourteen amino acid peptide and agonist of intestinal guanylate cyclase type C (GC-C), which is structurally related to the guanylin peptide family, with secretagogue, analgesic and laxative activities. Upon oral administration, linaclotide binds to and activates GC-C receptors located on the luminal surface of the intestinal epithelium. This increases the concentration of intracellular cyclic guanosine monophosphate (cGMP), which is derived from guanosine triphosphate (GTP). cGMP activates the cystic fibrosis transmembrane conductance regulator (CFTR) and stimulates the secretion of chloride and bicarbonate into the intestinal lumen. This promotes sodium excretion into the lumen and results in increased intestinal fluid secretion. This ultimately accelerates GI transit of intestinal contents, improves bowel movement and relieves constipation. Increased extracellular cGMP levels may also exert an antinociceptive effect, through an as of yet not fully elucidated mechanism, that may involve modulation of nociceptors found on colonic afferent pain fibers. Linaclotide is minimally absorbed from the GI tract.
Product detail pictures:
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Persisting in "High top quality, Prompt Delivery, Aggressive Price", now we have established long-term cooperation with customers from the two overseas and domestically and get new and aged clients' large comments for Factory best selling Protirelin Gmp Exporter From China - Linaclotide – JYMed , The product will supply to all over the world, such as: Mombasa, Serbia, Casablanca, Our solutions have national accreditation standards for experienced, premium quality items, affordable value, was welcomed by people around the globe. Our goods will continue to increase in the order and look forward to cooperation with you, Really should any of those products be of interest to you, please letus know. We are going to be pleased to give you a quotation up on receipt of one's detailed specifications.
By Raymond from Guinea - 2015.12.30 10:21
This supplier offers high quality but low price products, it is really a nice manufacturer and business partner.
By Andy from Irish - 2016.12.31 14:53
